Original Article
http://dx.doi.org/10.3349/ymj.2014.55.5.1326 pISSN: 0513-5796, eISSN: 1976-2437
Yonsei Med J 55(5):1326-1332, 2014
Role of 1,25-Dihydroxy Vitamin D3 and Parathyroid Hormone in Urinary Calcium Excretion in Calcium Stone Formers Won Tae Kim,1,3 Yong-June Kim,1 Seok Joong Yun,1 Kyung-Sub Shin,2 Young Deuk Choi,3 Sang Cheol Lee,1 and Wun-Jae Kim1 Departments of 1Urology and 2Laboratory Medicine, College of Medicine, Chungbuk National University, Cheongju; 3 Department of Urology, Graduate School of Medicine, Yonsei University, Seoul, Korea.
Received: October 7, 2013 Revised: December 26, 2013 Accepted: January 10, 2014 Corresponding author: Dr. Sang Cheol Lee, Department of Urology, College of Medicine, Chungbuk National University, 776 1sunhwan-ro, Heungdeok-gu, Cheongju 361-711, Korea. Tel: 82-43-269-6141, Fax: 82-43-269-6144 E-mail: [email protected] ∙ The authors have no financial conflicts of interest.
Purpose: To find out the possible role of 1,25(OH)2 vitamin D3 [1,25(OH)2D3] and parathyroid hormone (PTH) as intrinsic factors in urinary calcium stone formers (SFs), we investigated their relationship with serum and urinary biochemical parameters. Materials and Methods: A total of 326 calcium SFs (male: 204, female: 122) were enrolled and underwent outpatient metabolic evaluations including 1,25(OH)2D3 and PTH as well as serum and 24-hour urinary biochemical parameters. As control, 163 age- and sex-matched (2:1) individuals (non-SFs) who have never urinary stone episode were included. Results: 1,25(OH)2D3 level was positively correlated with urinary calcium excretion (r=0.347, p
http://dx.doi.org/10.3349/ymj.2014.55.5.1326 pISSN: 0513-5796, eISSN: 1976-2437
Yonsei Med J 55(5):1326-1332, 2014
Role of 1,25-Dihydroxy Vitamin D3 and Parathyroid Hormone in Urinary Calcium Excretion in Calcium Stone Formers Won Tae Kim,1,3 Yong-June Kim,1 Seok Joong Yun,1 Kyung-Sub Shin,2 Young Deuk Choi,3 Sang Cheol Lee,1 and Wun-Jae Kim1 Departments of 1Urology and 2Laboratory Medicine, College of Medicine, Chungbuk National University, Cheongju; 3 Department of Urology, Graduate School of Medicine, Yonsei University, Seoul, Korea.
Received: October 7, 2013 Revised: December 26, 2013 Accepted: January 10, 2014 Corresponding author: Dr. Sang Cheol Lee, Department of Urology, College of Medicine, Chungbuk National University, 776 1sunhwan-ro, Heungdeok-gu, Cheongju 361-711, Korea. Tel: 82-43-269-6141, Fax: 82-43-269-6144 E-mail: [email protected] ∙ The authors have no financial conflicts of interest.
Purpose: To find out the possible role of 1,25(OH)2 vitamin D3 [1,25(OH)2D3] and parathyroid hormone (PTH) as intrinsic factors in urinary calcium stone formers (SFs), we investigated their relationship with serum and urinary biochemical parameters. Materials and Methods: A total of 326 calcium SFs (male: 204, female: 122) were enrolled and underwent outpatient metabolic evaluations including 1,25(OH)2D3 and PTH as well as serum and 24-hour urinary biochemical parameters. As control, 163 age- and sex-matched (2:1) individuals (non-SFs) who have never urinary stone episode were included. Results: 1,25(OH)2D3 level was positively correlated with urinary calcium excretion (r=0.347, p
