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Scientific Programme

Plenary Lectures Sunday, May 11 2008 – 09.45–10.30 • Plenary Lecture 1 Klotho as a regulator of fibroblast growth factor signalling and phosphate/calcium metabolism Makoto Kuro-o, Dallas, USA Monday, May 12 2008 – 09.45–10.30 • Plenary Lecture 2 The fibroblast in progression of kidney diseases Eric Neilson, Nashville, USA Tuesday, May 13 2008 – 09.45–10.30 • Plenary Lecture 3 Is “essential hypertension” a kidney disease? Eberhard Ritz, Heidelberg, Germany

Free Communications & Mini Lectures Sunday, May 11 2008 – 08.00–09.30 • Free Communication + Mini Lecture 1 Transplantation 1 – Expansion of the living donor pool in Europe – ethical considerations Willem Weimar, Rotterdam, The Netherlands – 5 free communications Sunday, May 11 2008 – 08.00–09.30 • Free Communication + Mini Lecture 2 Glomerular diseases – Rituximab as a rescue therapy in ciclosporine dependent/resistant nephrotic syndrome Vincent Guigonis, Limoges, France – 5 free communications Sunday, May 11 2008 – 08.00–09.30 • Free Communication + Mini Lecture 3 Renal development – The molecular physiology of renal water handling Peter Deen, Nijmegen, The Netherlands – 5 free communications

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Sunday, May 11 2008 – 11.30–12.30 • Free Communication 4 Acute Kidney Injury 1 – 4 free communications Sunday, May 11 2008 – 11.30–12.30 • Free Communication 5 Diabetes 1 – 4 free communications Sunday, May 11 2008 – 11.30–12.30 • Free Communication 6 Cell signalling – 4 free communications Sunday, May 11 2008 – 14.30–16.00 • Free Communication 7 ERA–EDTA Fellows – 6 free communications Sunday, May 11 2008 – 14.30–16.00 • Free Communication + Mini Lecture 8 Chronic Kidney Disease – Molecular background of lipid disturbances in chronic kidney disease Michal Chmielewski, Gdansk, Poland – 5 free communications Sunday, May 11 2008 – 14.30–16.00 • Free Communication + Mini Lecture 9 Epidemiology 1 – Who and how should we screen for CKD in the elderly population? Ron Gansevoort, Groningen, The Netherlands – 5 free communications Sunday, May 11 2008 – 16.30–18.00 • Free Communication + Mini Lecture 10 Transplantation 2 – Proliferation signal inhibitors in renal transplantation, entering or leaving the field? Lionel Rostaing, Toulouse, France – 5 free communications Sunday, May 11 2008 – 16.30–18.00 • Free Communication + Mini Lecture 11 Cardiovascular diseases 1 – 6 free communications Sunday, May 11 2008 – 16.30–18.00 • Free Communication + Mini Lecture 12 Experimental pathology – Plasminogen activator inhibitor-1 in chronic kidney disease Agnes Fogo, Nashville, USA – 5 free communications

Scientific Programme

Scientific Programme

Monday, May 12 2008 – 8.00–9.30 • Free Communication + Mini Lecture 13 Bone Mineral Density – Chronic Kidney Disease – New genetic causes and mechanisms of urinary phosphate loss: implications for kidney stone and osteopenia Dominique Prié, Paris, France – 5 free communications Monday, May 12 2008 – 8.00–9.30 • Free Communication + Mini Lecture 14 Acute Kidney Injury 2 – Renal repair with stem cells – The future or an illusion? Enyu Imai, Osaka, Japan – 5 free communications Monday, May 12 2008 – 8.00–9.30 • Free Communication + Mini Lecture 15 Dialysis 1 – Impact of privatisation of dialysis units in Eastern Europe Laszlo Rosivall, Budapest, Hungary – 5 free communications Monday, May 12 2008 – 11.30–12.30 • Free Communication 16 Anaemia – 4 free communications Monday, May 12 2008 – 11.30–12.30 • Free Communication 17 Immune and inflammatory mechanisms – 4 free communications Monday, May 12 2008 – 11.30–12.30 • Free Communication 18 Inflammation and wasting – 4 free communications Monday, May 12 2008 – 14.30–16.00 • Free Communication + Mini Lecture 19 Biomarkers and progression – New insights into the mechanisms of proteinuria Erik Ilsø Christensen, Aarhus, Denmark – 5 free communications Monday, May 12 2008 – 14.30–16.00 • Free Communication + Mini Lecture 20 Genetics and Nephrology – The emerging role of epigenetics in health and disease Tomas Ekström, Stockholm, Sweden – 5 free communications

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Monday, May 12 2008 – 14.30–16.00 • Free Communication + Mini Lecture 21 Acid base and ions transport – The molecular physiology of renal calcium handling René Bindels, Nijmegen, The Netherlands – 5 free communications Monday, May 12 2008 – 16.30–18.00 • Free Communication + Mini Lecture 22 Dialysis 2 – How to measure peritoneal transport? Raymond Krediet, Amsterdam, The Netherlands – 5 free communications Monday, May 12 2008 – 16.30–18.00 • Free Communication + Mini Lecture 23 Cardiovascular diseases 2 – Sleep apnoea in renal transplantation Francesca Mallamaci, Reggio Calabria, Italy – 5 free communications Monday, May 12 2008 – 16.30–18.00 • Free Communication + Mini Lecture 24 Vascular physiology and hypertension – New insights in capillary physiology Bengt Rippe, Lund, Sweden – 5 free communications Tuesday, May 13 2008 – 8.00–9.30 • Free Communication + Mini Lecture 25 Transplantation 3 – Drugs and glucose metabolism in the transplant patient Francesco Paolo Schena, Bari, Italy – 5 free communications Tuesday, May 13 2008 – 8.00–9.30 • Free Communication + Mini Lecture 26 Pathophysiology and clinical studies – New insights into the pathophysiology of urinary tract infection: role of argininine vasopressin Alain Vandewalle, Paris, France – 5 free communications Tuesday, May 13 2008 – 8.00–9.30 • Free Communication + Mini Lecture 27 Diabetes 2 – Novel therapeutic approaches to diabetic nephropathy Toshio Miyata, Isehara, Japan – 5 free communications

Scientific Programme

Scientific Programme

Tuesday, May 13 2008 – 11.30–12.30 • Free Communication + Mini Lecture 28 Cardiovascular diseases 3 – Prevention of cardiovascular complications after renal transplantation. Who and how do we treat Hallvard Holdaas, Oslo, Norway – 3 free communications Tuesday, May 13 2008 – 11.30–12.30 • Free Communication 29 Epidemiology 2 – 4 free communications

Symposia Sunday, May 11 2008 – 08.00–09.30 • Symposium 1 Phosphatonins – from nucleus to the patient – Molecular physiology of renal phosphate reabsorption Heini Murer, Zurich, Switzerland – Phosphatonins – basic science and clinical aspects Rajiv Kumar, Rochester, USA – FGF-23 in CKD-MBD Östen Ljunggren, Uppsala, Sweden – FGF-23 in CKD, ectopic calcification, posttransplantation-hypophosphatemia, and nephrolitiasis Masafumi Fukagawa, Kobe, Japan Sunday, May 11 2008 – 08.00–09.30 • Symposium 2 Hyponatraemia – The biology and physiology of aquaporins Søren Nielsen, Aarhus, Denmark – The incidence and prevalence of hyponatremia Andrzej Wieçek, Katowice, Poland – The traditional management of acute hyponatremia Tevfik Ecder, Istanbul, Turkey – Vasopressin antagonists: do they change the prognosis? Peter Gross, Dresden, Germany Sunday, May 11 2008 – 11.30–12.30 • Symposium 3 RRT in cardiac failure – The cardio-renal syndrome – An update Charles A. Herzog, Minneapolis, USA – Atrial volume and atrial biomarkers: a risk stratification criterium in dialysis patients Bernard Canaud, Montpellier, France – Which RRT in heart failure Adrian Covic, Iasi, Romania

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Sunday, May 11 2008 – 11.30–12.30 • Symposium 4 The kidney in pregnancy – Normal renal physiology in pregnancy Jacques Bernheim, Kfar Saba, Israel – Pathophysiology of pre-eclampsia Michelle Hladunewich, Toronto, Canada – Pre pregnancy counselling for women with CKD Liz Lightstone, London, UK Sunday, May 11 2008 – 11.30–12.30 • Symposium 5 Eutox – New elements in the role of ureamic toxins in arteriosclerosis Raymond Vanholder, Ghent, Belgium – Uraemic toxicity and cardiovascular calcifications Ziad Massy, Amiens, France – Homocysteine is linked to DNA hypomethylation Alessandra Perna, Naples, Italy Sunday, May 11 2008 – 11.30–12.30 • Symposium 6 Modifiable Treatment Factors and Outcomes in Dialysis: DOPPS and Cosmos – COSMOS: A picture of CKD-MBD in the European scenario Jorge Cannata-Andía, Oviedo, Spain – Outcomes associated with modifiable dialysis unit practices in the DOPPS Stefan H. Jacobson, Stockholm, Sweden – New DOPPS findings on anaemia practices and outcomes Bruce Robinson, Ann Arbor, USA Sunday, May 11 2008 – 14.30–16.00 • Symposium 7 Metabolic Syndrome – Definition and epidemiology of the metabolic syndrome Anders Alvestrand, Stockholm, Sweden – Insulin resistance in hypertension and kidney disease Pantelis A. Sarafidis, Thessaloniki, Greece – Obesity as risk factor for CKD Stephan J. L. Bakker, Groningen, The Netherlands – To what extent should we treat obesity in dialysis patients? Renée de Mutsert, Leiden, The Netherlands Sunday, May 11 2008 – 14.30–16.00 • Symposium 8 Paediatric Nephrology – Fetal programming and CKD in adults Karl Skorecki, Haifa, Israel – Human renal dysplasia syndromes: mixing cell biology and genetics Adrian Woolf, London, UK – Congenital nephrotic syndromes Karl Tryggvason, Stockholm, Sweden – New hereditary basement membrane diseases: the brain–eye–kidney connection Emmanuelle Plaisier, Paris, France

Scientific Programme

Scientific Programme

Sunday, May 11 2008 – 16.30–18.00 • Symposium 9 Management of glomerular diseases – Thrombotic microangiopathies Giuseppe Remuzzi, Bergamo, Italy – IgA nephropathy John Feehally, Leicester, UK – Renal and systemic vasculitis Caroline Savage, Birmingham, UK – Renal amyloidosis and monoclonal deposition diseases Pierre Ronco, Paris, France Sunday, May 11 2008 – 16.30–18.00 • Symposium 10 Pathophysiology of AKI – Microvascular alterations in AKI Bruce A. Molitoris, Indianapolis, USA – Tissue protection in ischaemia Danilo Fliser, Homburg/Saar, Germany – Role of inflammatory cells in AKI Marc De Broe, Antwerp, Belgium – Role of HIF in AKI Kai-Uwe Eckardt, Erlangen, Germany Monday, May 12 2008 – 08.00–09.30 • Symposium 11 Current problems in transplantation – What can the clinician learn from protocol biopsies? Michael J. Mihatsch, Basel, Switzerland – Management of chronic allograft nephropathy Bengt Fellstrom, Uppsala, Sweden – The marginal kidney donor Ulrich Frei, Berlin, Germany – Current problems in transplantation in children Christer Holmberg, Helsinki, Finland Monday, May 12 2008 – 08.00–09.30 • Symposium 12 ADPKD and other hereditary diseases – Recent molecular biological insights in the pathogenesis of ADPKD Olivier Devuyst, Brussels, Belgium – Therapy with vasopressin antagonists in ADPKD Vicente Torres, Rochester, USA – Therapy with somatostatin analogues in ADPKD Piero Ruggenenti, Bergamo, Italy – Mechanisms of injury in uromodulin-associated kidney disease Matthias Wolf, Dallas, USA

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Monday, May 12 2008 – 08.00–09.30 • Symposium 13 Vascular Biology – Basic and clinical aspects – Molecular mechanisms in vascular calcification Markus Ketteler, Coburg, Germany – The (pro)renin receptor in cardiovascular and kidney disease Geneviève Nguyen, Paris, France – Aldosterone and mineralocorticoid receptors in vascular remodelling Anette Fiebeler, Berlin, Germany – Clinical assessment of endothelial dysfunction Michael S. Goligorsky, New York, USA Monday, May 12 2008 – 11.30–12.30 • Symposium 14 CKD as a public health problem – Who and how to screen for CKD? Stein Hallan, Trondheim, Norway – Early identification of CKD: the primary care physician–nephrologist interface Paul Stevens, Canterbury, UK – CKD originating in pregnancy and in childhood Guido Filler, London, Canada Monday, May 12 2008 – 11.30–12.30 • Symposium 15 Lupus and the kidney – Classification of Lupus Nephritis Jan J. Weening, Blaricum, the Netherlands – Experimental models of Lupus Nephritis Terry Cook, London, UK – Induction and maintenance therapy Claudio Ponticelli, Milan, Italy Monday, May 12 2008 – 11.30–12.30 • Symposium 16 Dialysis in the diabetic patient – Antidiabetic treatment in diabetic patients with kidney disease Guntram Schernthaner, Vienna, Austria – The diabetic foot – diagnosis of the foot at risk and management of foot complications Kerstin Brismar, Stockholm, Sweden – Rehabilitation and physical exercise of diabetic kidney patients Naomi Clyne, Lund, Sweden Monday, May 12 2008 – 11.30–12.30 • Symposium 17 KDIGO – Overview of the KDIGO CKD-MBD Guidelines – part 1 Tilman Drüeke, Paris, France – Overview of the KDIGO CKD-MBD Guidelines – part 2 David Wheeler, London, UK

Scientific Programme

Scientific Programme

Monday, May 12 2008 – 14.30–16.00 • Symposium 18 The care of the ICU patient with ARF – Nutritional aspects of the critically ill ARF patients Emmanuel Burdmann, Sao Jose do Rio Preto, Brazil – Timing of initiation and stopping of RRT in ARF Wilfred Druml, Vienna, Austria – Modality of RRT selection for AKI in the ICU Michael Schneider, Berlin, Germany – AKI in critically ill paediatric patients Stefano Picca, Rome, Italy Monday, May 12 2008 – 14.30–16.00 • Symposium 19 Immunosuppression in kidney transplantation – Update on the immunobiology in kidney transplantation Daniel Abramowicz, Brussels, Belgium – New immunosuppressive drugs on the horizon Flavio Vincenti, San Francisco, USA – Limited steroid protocols David Taube, London, UK – Calcineurin-free protocols Yves Vanrenterghem, Leuven, Belgium Monday, May 12 2008 – 14.30–16.00 • Symposium 20 The podocyte and its diseases – Podocytes: surface proteins and cytoskeleton network Harry Holthöfer, Helsinki, Finland – Podocytes in FSGS Peter Mathieson, Bristol, UK – Podocytes and IgA Nephropathy Rosanna Coppo, Turin, Italy – The podocyte in diabetic nephropathy Paola Fioretto, Padua, Italy Monday, May 12 2008 – 16.30–18.00 • Symposium 21 The bone in the kidney transplant – Intracellular mechanisms of bone remodelling Marie-Helene Lafage Proust, Saint-Etienne, France – An update on post-transplant bone disease João M Frazão, Porto, Portugal – What is the role of biphosphonates following kidney transplantation? John Cunningham, London, UK – Calcimimetics and vit D after kidney transplantation Rudolf Wüthrich, Zurich, Switzerland

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Monday, May 12 2008 – 16.30–18.00 • Symposium 22 Innate immunology and the kidney – Innate immunity and kidney disease Detlef Schlöndorff, New York, USA – Toll-like receptors in immune complex glomerulonephritis Hans Joachim Anders, Munich, Germany – The role of the fibrinolytic system in renal ischemia-reperfusion injury Sandrine Florquin, Amsterdam, The Netherlands – Recent insights in complement-induced kidney diseases Jürgen Floege, Aachen, Germany Tuesday, May 13 2008 – 08.00–09.30 • Symposium 23 Hypertension – Definition, epidemiology and management of pre-hypertension Dogan Erdogan, Konya, Turkey – Drug therapy in uncomplicated hypertension – effects on organ damage Ola Samuelsson, Gothenburg, Sweden – Hypertension in the elderly Robert Fagard, Leuven, Belgium – Intensified blood pressure control slows CKD progression in children. Final results of ESCAPE Trial Franz Schaefer, Heidelberg, Germany Tuesday, May 13 2008 – 08.00–09.30 • Symposium 24 The difficult patient on dialysis – The adolescent and transitional nephrology Alan Watson, Nottingham, UK – The depressed patient in dialysis Paul Kimmel, Washington, USA – The frail elderly Edwina Brown, London, UK – The failed transplant patient Mehmet Sever, Istanbul, Turkey Tuesday, May 13 2008 – 08.00–09.30 • Symposium 25 Protein-energy wasting in ESRD – Protein-energy wasting in CKD Denis Fouque, Lyon, France – Energy expenditure in HD and PD Lilian Cuppari, Sao Paulo, Brazil – Inflammation and protein-energy wasting in CKD – Partners in crime Peter Stenvinkel, Stockholm, Sweden – Nutritional interventions in the advanced CKD patients with PEW Talat Alp Ikizler, Nashville, USA

Scientific Programme

Scientific Programme

Tuesday, May 13 2008 – 11.30–12.30 • Symposium 26 Actual problems in dialysis – Evaluation of the vascular access Jan H. Tordoir, Maastricht, The Netherlands – New tests for evaluation of peritoneal transport Vincenzo La Milia, Lecco, Italy – Integration of PD and HD programmes Simon J. Davies, Stoke-on-Trent, UK Tuesday, May 13 2008 – 11.30–12.30 • Symposium 27 Pro–Con Debate on new PD solutions – Pro – Solutions can be a solution for PD related problems Wim Van Biesen, Ghent, Belgium – Con – New biocompatible PD solutions have no evident clinical benefit Olof Heimbürger, Stockholm, Sweden Tuesday, May 13 2008 – 11.30–12.30 • Symposium 28 Oncology and the kidney – Hypercalcaemia in the oncology patient Goce Spasovski, Skopje, F.Y.R. of Macedonia – Renal side effects of anti-VEGF therapy Gilbert Deray, Paris, France – Relationships between CKD and malignancies Benedicte Stengel, Villejuif, France Tuesday, May 13 2008 – 11.30–12.30 • Symposium 29 Last minute trials – Results of Renal-ONTARGET Johannes F.E. Mann, Munich, Germany – Revascularisation for atherosclerotic renovascular disease: results of the ASTRAL trial Philip Kalra, Salford, UK – Mycophenolate mofetil or intravenous cyclophosphamide as induction for lupus nephritis: ALMS renal endpoints David Jayne, Cambridge, UK – The MPO Study: is it more than an European HEMO study? Francesco Locatelli, Lecco, Italy Tuesday, May 13 2008 – 11.30–12.30 • Symposium 30 Pro–Con Debate: Do we need Clinical Practice Guidelines? – Pro Garabed Eknoyan, Houston, USA – Con David Goldsmith, London, UK

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Compact Primers Sunday, May 11 2008 – 08.00–09.30 • Compact Primer 1 The nephrologist in the ICU – What the nephrologist needs to know about artificial ventilation Miet Schetz, Leuven, Belgium – Haemodynamic monitoring and volume management in the critically ill Claus Krenn, Vienna, Austria – Severe sepsis, septic shock and the kidney Eric Hoste, Ghent, Belgium – Clinical features and treatment options for ARDS? Zaccaria Ricci, Rome, Italy Monday, May 12 2008 – 08.00–09.30 • Compact Primer 2 Observational studies in Nephrology: under STROBE scrutiny – Observational studies revisited: designs, strengths and weaknesses Kitty Jager, Amsterdam, the Netherlands – When are observational studies as strong as RCTs? Friedo Dekker, Leiden, the Netherlands – Guidelines for reporting observational studies: the newly published STROBE statement Carmine Zoccali, Reggio Calabria, Italy Monday, May 12 2008 – 14.30–16.00 • Compact Primer 3 Selective Vitamin D receptors – Mechanisms of renal and cardiovascular actions of Vit D receptors Klaus Olgaard, Copenhagen, Denmark – Vitamin D in CKD: 25 D, 1,25 D, or both? Ravi Thadhani, Boston, USA – Treatment of uraemic patients with vitamin D receptor activators Tilman Drüeke, Paris, France – The differences between the several therapeutic molecules Adeera Levin, Vancouver, Canada Tuesday, May 13 2008 – 08.00–09.30 • Compact Primer 4 Imaging in nephrology – Can we measure renal tissue perfusion by ultrasound? Thomas Scholbach, Leipzig, Germany – Angio or MRI: advice for the nephrologist Peter Aspelin, Stockholm, Sweden – Gadolinium-based MR contrast agents and nephrogenic systemic fibrosis Peter Marckmann, Herlev, Denmark – Can we measure vascular calcification in the office? Gérard London, Fleury-Merogis, France

Scientific Programme

Scientific Programme

Literature Updates Sunday, May 11 2008 – 14.30–16.00 • Literature Update 1 Clinical Nephrology I – Glomerular diseases and vasculitis Vladimir Tesar, Prague, Czech Republic – Cardiovascular disease and CKD Jeroen Kooman, Maastricht, the Netherlands – Diabetic nephropathy David Wheeler, London, UK Sunday, May 11 2008 – 16.30–18.00 • Literature Update 2 Haemodialysis and Peritoneal dialysis – Haemodialysis Robert Mactier, Glasgow, UK – Peritoneal dialysis Rafael Selgas, Madrid, Spain – Quality of Life issues in dialysis Fredric O. Finkelstein, New Haven, USA Monday, May 12 2008 – 16.30–18.00 • Literature Update 3 Clinical Nephrology II – Metabolic impact of CKD Christoph Wanner, Würzburg, Germany – Bone and vascular mineral disorders Albert Fournier, Amiens, France – Renal anaemia – A 2008 update Iain C. Macdougall, London, UK Monday, May 12 2008 – 16.45–18.15 • Literature Update 4 Transplantation – Immunosuppression in renal transplantation Josep M. Grinyo, Barcelona, Spain – Malignancies after transplantation Ulrich Kunzendorf, Kiel, Germany – Opportunistic infections Jürg Ulrich Steiger, Basel, Switzerland

CME Courses 1. Home dialysis therapies Edwina Brown, London, UK Wim Van Biesen, Ghent, Belgium 2. Rehabilitation in CKD Patients Rolfdieter Krause, Berlin, Germany Asterios Deligiannis, Thessaloniki, Greece

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3. How to manage difficult cases of Lupus Nephritis Agnes Fogo, Nashville, USA David Jayne, Cambridge, UK Franco Ferrario, Milan, Italy 4. Dialysis access Jan H. Tordoir, Maastricht, The Netherlands 5. A primer on basic science methods relevant to Nephrology Jürgen Floege, Aachen, Germany Rosanna Coppo, Turin, Italy

Special Pre-Congress Meeting • The epidemiology of CKD in Europe: National Surveys and Initiatives Paul De Jong, Groningen, The Netherlands Carmine Zoccali, Reggio Calabria, Italy

Scientific Programme