SECRETION OF PROSTAGLANDIN F2o~ IN CYCLING A N D PREGNANT EWES 1 ,2
Colorado State University 6, Fort Collins 8 0 5 2 3
SUMMARY
Indwelling cannulas were placed into a branch of the uterine vein and int.o the uteroovarian vein of 10 nonpregnant ewes and into the utero-ovarian vein only of eight pregnant ewes. Blood samples were collected into chilled, heparinized tubes at 3-hr intervals from days 11 to 14 (three pregnant and five cycling ewes) or from days 14 to 17 (five pregnant and five cycling ewes) after estrus. Levels of prostaglandin (PG) F2~ were determined by radioimmunoassay. No significant difference was noted in mean levels of PGF2a in the utero-ovarian vein between cycling (9.1 + .6 ng/ml, n=458) and pregnant (8.1 + .1 ng/ml, n=386) ewes. However, there was more variation (P
Colorado State University 6, Fort Collins 8 0 5 2 3
SUMMARY
Indwelling cannulas were placed into a branch of the uterine vein and int.o the uteroovarian vein of 10 nonpregnant ewes and into the utero-ovarian vein only of eight pregnant ewes. Blood samples were collected into chilled, heparinized tubes at 3-hr intervals from days 11 to 14 (three pregnant and five cycling ewes) or from days 14 to 17 (five pregnant and five cycling ewes) after estrus. Levels of prostaglandin (PG) F2~ were determined by radioimmunoassay. No significant difference was noted in mean levels of PGF2a in the utero-ovarian vein between cycling (9.1 + .6 ng/ml, n=458) and pregnant (8.1 + .1 ng/ml, n=386) ewes. However, there was more variation (P
