Archives of Physical Medicine and Rehabilitation journal homepage: www.archives-pmr.org Archives of Physical Medicine and Rehabilitation 2015;96:913-9
ORIGINAL RESEARCH
Self-Efficacy as a Longitudinal Predictor of Perceived Cognitive Impairment in Individuals With Multiple Sclerosis Abbey J. Hughes, PhD,a,b Meghan Beier, PhD,a Narineh Hartoonian, PhD,b Aaron P. Turner, PhD,a,b Dagmar Amtmann, PhD,a Dawn M. Ehde, PhDa From the aDepartment of Rehabilitation Medicine, University of Washington, Seattle, WA; and bMultiple Sclerosis Center of Excellence West, Veterans Affairs Puget Sound Health Care System, Seattle, WA.
Abstract Objectives: To determine whether self-efficacy longitudinally predicts 2 types of perceived cognitive impairment (PCI) in multiple sclerosis (MS): general cognitive functioning and executive functioning; and secondarily to assess whether self-efficacy mediates the relationships between depression, fatigue, and PCI. Design: Longitudinal analysis of self-report survey data collected over 3 years. Hierarchical regression analyses examined the relationship between self-efficacy and PCI, adjusting for depression and fatigue. Additional analyses tested self-efficacy as a mediator between depression, fatigue, and PCI. Setting: Community. Participants: Community-dwelling individuals with MS (NZ233; age range, 22e83y) were recruited from a larger longitudinal survey study of individuals with MS (NZ562). Interventions: Not applicable. Main Outcome Measures: Primary outcome measures were the Applied CognitioneGeneral Concerns and the Applied CognitioneExecutive Function domains of the Quality of Life in Neurological Disorders (NeuroQoL) measures. Results: Self-efficacy was significantly correlated with PCI at baseline (rZ.40e.53) and 3 years later (rZ.36e.44). In multivariate regression analyses, self-efficacy was a significant longitudinal predictor of PCI, both for general cognitive functioning (bZ.20, P
ORIGINAL RESEARCH
Self-Efficacy as a Longitudinal Predictor of Perceived Cognitive Impairment in Individuals With Multiple Sclerosis Abbey J. Hughes, PhD,a,b Meghan Beier, PhD,a Narineh Hartoonian, PhD,b Aaron P. Turner, PhD,a,b Dagmar Amtmann, PhD,a Dawn M. Ehde, PhDa From the aDepartment of Rehabilitation Medicine, University of Washington, Seattle, WA; and bMultiple Sclerosis Center of Excellence West, Veterans Affairs Puget Sound Health Care System, Seattle, WA.
Abstract Objectives: To determine whether self-efficacy longitudinally predicts 2 types of perceived cognitive impairment (PCI) in multiple sclerosis (MS): general cognitive functioning and executive functioning; and secondarily to assess whether self-efficacy mediates the relationships between depression, fatigue, and PCI. Design: Longitudinal analysis of self-report survey data collected over 3 years. Hierarchical regression analyses examined the relationship between self-efficacy and PCI, adjusting for depression and fatigue. Additional analyses tested self-efficacy as a mediator between depression, fatigue, and PCI. Setting: Community. Participants: Community-dwelling individuals with MS (NZ233; age range, 22e83y) were recruited from a larger longitudinal survey study of individuals with MS (NZ562). Interventions: Not applicable. Main Outcome Measures: Primary outcome measures were the Applied CognitioneGeneral Concerns and the Applied CognitioneExecutive Function domains of the Quality of Life in Neurological Disorders (NeuroQoL) measures. Results: Self-efficacy was significantly correlated with PCI at baseline (rZ.40e.53) and 3 years later (rZ.36e.44). In multivariate regression analyses, self-efficacy was a significant longitudinal predictor of PCI, both for general cognitive functioning (bZ.20, P
![[Pathogenesis of cognitive impairment in multiple sclerosis].](/assets/img/hold.png)
