CLINICAL RESEARCH e-ISSN 1643-3750 © Med Sci Monit, 2014; 20: 1151-1154 DOI: 10.12659/MSM.890472
Serum adenosine deaminase activity in cutaneous anthrax
Received: 2014.01.31 Accepted: 2014.03.11 Published: 2014.07.06
Authors’ Contribution: Study Design A Data Collection B Analysis C Statistical Data Interpretation D Manuscript Preparation E Literature Search F Collection G Funds
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Mahmut Sunnetcioglu Sevdegul Karadas Mehmet Aslan Mehmet Resat Ceylan Halit Demir Mehmet Resit Oncu Mustafa Kasım Karahocagil Aysel Sunnetcioglu Cenk Aypak
1 Department of Infectious Diseases and Clinical Microbiology, Yuzuncu Yil University, Faculty of Medicine, Van, Turkey 2 Department of Emergency Medicine, Yuzuncu Yil University, Faculty of Medicine, Van, Turkey 3 Department of Internal Medicine, Yuzuncu Yil University, Faculty of Medicine, Van, Turkey 4 Department of Chemistry, Yuzuncu Yil University, Faculty of Science and Art, Van, Turkey 5 Department of Pulmonary Diseases, Yuzuncu Yil University, Faculty of Medicine, Van, Turkey 6 Department of Family Medicine, Diskapi Yildirim Beyazit Training and Research Hospital, Ankara, Turkey
Cenk Aypak, e-mail: [email protected] Departmental sources
Adenosine deaminase (ADA) activity has been discovered in several inflammatory conditions; however, there are no data associated with cutaneous anthrax. The aim of this study was to investigate serum ADA activity in patients with cutaneous anthrax. Sixteen patients with cutaneous anthrax and 17 healthy controls were enrolled. We measured ADA activity; peripheral blood leukocyte, lymphocyte, neutrophil, and monocyte counts; erythrocyte sedimentation rate; and C reactive protein levels. Serum ADA activity was significantly higher in patients with cutaneous anthrax than in the controls (p0.05) (Table 1). Blood leukocyte counts were significantly higher in the patients with cutaneous anthrax compared with the controls (p=0.037). Although lymphocyte and neutrophil counts were higher in the patient group, there were no statistically significant differences (p>0.05). ESR and CRP levels were significantly higher in the patients with cutaneous anthrax compared with the controls (p
Serum adenosine deaminase activity in cutaneous anthrax
Received: 2014.01.31 Accepted: 2014.03.11 Published: 2014.07.06
Authors’ Contribution: Study Design A Data Collection B Analysis C Statistical Data Interpretation D Manuscript Preparation E Literature Search F Collection G Funds
ABCDEF 1 ABDEF 2 ABDEF 1,3 ABCDEF 1 ABCDE 4 ABDEF 2
ABCDE 1
ABCDEF 5
ACDEF 6
Corresponding Author: Source of support:
Background:
Material/Methods:
Results:
Conclusions:
MeSH Keywords:
Full-text PDF:
Mahmut Sunnetcioglu Sevdegul Karadas Mehmet Aslan Mehmet Resat Ceylan Halit Demir Mehmet Resit Oncu Mustafa Kasım Karahocagil Aysel Sunnetcioglu Cenk Aypak
1 Department of Infectious Diseases and Clinical Microbiology, Yuzuncu Yil University, Faculty of Medicine, Van, Turkey 2 Department of Emergency Medicine, Yuzuncu Yil University, Faculty of Medicine, Van, Turkey 3 Department of Internal Medicine, Yuzuncu Yil University, Faculty of Medicine, Van, Turkey 4 Department of Chemistry, Yuzuncu Yil University, Faculty of Science and Art, Van, Turkey 5 Department of Pulmonary Diseases, Yuzuncu Yil University, Faculty of Medicine, Van, Turkey 6 Department of Family Medicine, Diskapi Yildirim Beyazit Training and Research Hospital, Ankara, Turkey
Cenk Aypak, e-mail: [email protected] Departmental sources
Adenosine deaminase (ADA) activity has been discovered in several inflammatory conditions; however, there are no data associated with cutaneous anthrax. The aim of this study was to investigate serum ADA activity in patients with cutaneous anthrax. Sixteen patients with cutaneous anthrax and 17 healthy controls were enrolled. We measured ADA activity; peripheral blood leukocyte, lymphocyte, neutrophil, and monocyte counts; erythrocyte sedimentation rate; and C reactive protein levels. Serum ADA activity was significantly higher in patients with cutaneous anthrax than in the controls (p0.05) (Table 1). Blood leukocyte counts were significantly higher in the patients with cutaneous anthrax compared with the controls (p=0.037). Although lymphocyte and neutrophil counts were higher in the patient group, there were no statistically significant differences (p>0.05). ESR and CRP levels were significantly higher in the patients with cutaneous anthrax compared with the controls (p
