British Journal of Rheumatology 1991 ;30:451-454

CLINICAL PRACTICE

SHOULD DISEASE-MODIFYING AGENTS BE USED IN MILD RHEUMATOID ARTHRITIS? BY M. J. DAVIS, P. T. DAWES, P. D. FOWLER, S. CLARKE, J. FISHER AND M. F. SHADFORTH Staffordshire Rheumatology Centre, Stoke-on-Trent

SUMMARY A 12-month double-blind controlled study comparing hydroxychloroquine 400 mg daily with placebo in 104 patients with mild RA was conducted to see whether patients with mild rheumatoid arthritis (RA) benefit from treatment with diseasemodifying agents. Mild RA was denned as synovitis limited to the hands and feet, an ESR

Should disease-modifying agents be used in mild rheumatoid arthritis?

A 12-month double-blind controlled study comparing hydroxychloroquine 400 mg daily with placebo in 104 patients with mild RA was conducted to see whet...
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