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BJO Online First, published on January 2, 2015 as 10.1136/bjophthalmol-2014-305962 Clinical science
Significance of corneal biomechanical properties in patients with progressive normal-tension glaucoma Jong Hyuk Park, Roo Min Jun, Kyu-Ryong Choi Department of Ophthalmology, Institute of Ophthalmology & Optometry, Ewha Womans University School of Medicine, Seoul, Republic of Korea Correspondence to Dr Kyu-Ryong Choi, Department of Ophthalmology, Ewha Womans University Mokdong Hospital, 911-1, Mok-dong Yangcheon-ku, Seoul 158-710, Republic of Korea; [email protected] Received 6 August 2014 Revised 3 December 2014 Accepted 5 December 2014
ABSTRACT Aim To investigate the clinical significance of corneal biomechanical properties assessed using an ocular response analyser in patients with progressing normaltension glaucoma (NTG). Methods In this retrospective study, we included 82 eyes of 82 NTG patients who had been receiving topical anti-glaucoma medications. Patients were allocated to two groups based on the mean value of corneal hysteresis (CH) and the status of progression. The assessment of progression was based on the trend analysis using mean deviation slope. Uni- and multivariable logistic analyses were constructed to identify factors associated with increased odds of progression, including CH, central corneal thickness (CCT), and retinal nerve fibre layer (RNFL) thickness. Results Forty-six eyes (56.1%) reached the progression criteria. Eyes with progression had lower CCT (530.2 ±38.6 vs 549.4±38.3 μm, p=0.03), thinner average RNFL thickness (70.6±16.1 vs 82.8±17.4 μm, p
BJO Online First, published on January 2, 2015 as 10.1136/bjophthalmol-2014-305962 Clinical science
Significance of corneal biomechanical properties in patients with progressive normal-tension glaucoma Jong Hyuk Park, Roo Min Jun, Kyu-Ryong Choi Department of Ophthalmology, Institute of Ophthalmology & Optometry, Ewha Womans University School of Medicine, Seoul, Republic of Korea Correspondence to Dr Kyu-Ryong Choi, Department of Ophthalmology, Ewha Womans University Mokdong Hospital, 911-1, Mok-dong Yangcheon-ku, Seoul 158-710, Republic of Korea; [email protected] Received 6 August 2014 Revised 3 December 2014 Accepted 5 December 2014
ABSTRACT Aim To investigate the clinical significance of corneal biomechanical properties assessed using an ocular response analyser in patients with progressing normaltension glaucoma (NTG). Methods In this retrospective study, we included 82 eyes of 82 NTG patients who had been receiving topical anti-glaucoma medications. Patients were allocated to two groups based on the mean value of corneal hysteresis (CH) and the status of progression. The assessment of progression was based on the trend analysis using mean deviation slope. Uni- and multivariable logistic analyses were constructed to identify factors associated with increased odds of progression, including CH, central corneal thickness (CCT), and retinal nerve fibre layer (RNFL) thickness. Results Forty-six eyes (56.1%) reached the progression criteria. Eyes with progression had lower CCT (530.2 ±38.6 vs 549.4±38.3 μm, p=0.03), thinner average RNFL thickness (70.6±16.1 vs 82.8±17.4 μm, p
![[Evaluation of corneal biomechanical properties in glaucoma and control patients by dynamic Scheimpflug corneal imaging technology].](/assets/img/hold.png)
