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Holeva V, Tarrier N, Wells A. Prevalence and predictors of acute stress disorder and PTSD following road traffic accidents: thought control strategies and social support. Behav Ther 2001; 32: 65–83. National Institute for Health Care Excellence. Post-traumatic stress disorder (PTSD). The management of PTSD in adults and children in primary and secondary care. NICE clinical guideline 26. National Institute for Health Care Excellence, March 2005. Sijbrandij M, Kleiboer A, Bisson JI, Barbui C, Cuijpers P. Pharmacological prevention of post-traumatic stress disorder and acute stress disorder: a systematic review and meta-analysis. Lancet Psychiatry 2015; published online April 14. http://dx.doi.org/10.1016/S2215-0366(14)00121-7.

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Rothman KJ, Lash TL, Greenland S, eds. Modern epidemiology. Philadelphia: Lippincott Williams and Wilkins, 3rd edn, 2013. Triplett KN, Tedeschi RG, Cann A, Calhoun LG, Reeve CL. Posttraumatic growth, meaning in life, and life satisfaction in response to trauma. Psychol Trauma Theory Res Pract Policy 2012; 4: 400–10. Schnurr PP, Lunney CA, Bovin MJ, Marx BP. Posttraumatic stress disorder and quality of life: Extension of findings to veterans of the wars in Iraq and Afghanistan. Clinical Psychol Rev 2009; 29: 727–35.

Substance use disorders and avoidable mortality after prison Worldwide, more than 30 million people spend time in prison every year.1 The USA incarcerates 25% of these people and one in 31 Americans is currently under correctional control, either in jail, prison, or on probation or parole.2 Most prisoners will eventually be released, and the 2 weeks after release have been shown to be associated with a substantial increase in mortality, especially from overdose.3 Substance use disorders are highly prevalent among incarcerated populations, with more than half of prisoners in some countries being imprisoned for drug-related convictions.4 In the USA, 85% of people in prisons or jails are substance involved, with 1·5 million individuals meeting DSM criteria for a substance use disorder and an additional 458 000 either with a history of substance use, under the influence at the time of arrest, or convicted of a crime committed to obtain money to buy drugs.5 Addiction is a treatable disease and decades of scientific evidence support the efficacy of treatment to improve clinical outcomes, save lives, and reduce societal costs. Treatment for opioid use disorder during incarceration with agonists such as buprenorphine or methadone has been shown to reduce recidivism, improve treatment retention, reduce illicit drug use, and decrease criminal activity.6,7 Buprenorphine has also been shown to decrease the risk of overdose death by more than 50%.8 However, despite the overwhelming evidence, treatment remains variable between correctional facilities and few prisoners receive these life-saving drugs.9 In The Lancet Psychiatry, Zheng Chang and colleagues10 examined mortality in all people released from prison in Sweden between Jan 1, 2000, and Dec 31, 2009. In this sample of 47 326 individuals and 238 457 person-years of follow-up, the researchers www.thelancet.com/psychiatry Vol 2 May 2015

reported that substance use (both alcohol and illicit drug use) was related to a substantial proportion of post-release mortality, even when controlling for other factors using imprisoned siblings as controls. The association between mental illness and postrelease mortality disappeared when substance use was controlled for. This well designed study of an entire country offers important and concerning new data on the high risk of death for individuals with substance use disorder who are incarcerated. The results of the study also showed that the period of risk of increased mortality after release from prison is much longer— months to years—than the few weeks previously reported,3 an important finding that is probably true in most places. These findings are even more alarming when considering the magnitude of risk for a country such as the USA, which has a much higher incarceration rate and far more drug-related convictions than does Sweden. Access to effective treatments for addiction, particularly pharmacotherapy, is the single greatest intervention that can reduce the death toll from overdose.11 The withholding of evidence-based treatment for prisoners is arguably unethical and certainly unwise. In the USA, correctional facilities are mandated by the Supreme Court to provide medical care that meets the community standard.12 And yet, within state prisons people with drug use disorders largely go without care: of these people, only 0·8% receive detoxification services, 0·3% receive maintenance pharmacotherapy, 6·5% receive counselling by a professional, and 9·5% receive treatment in a residential facility.13 Even those on treatment in the community are systematically forced off when incarcerated, with detrimental consequences.14 The absence of care in this deeply

Published Online April 22, 2015 http://dx.doi.org/10.1016/ S2215-0366(15)00125-X See Articles page 422

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affected population translates into high costs to society and the communities that these individuals return to. As the Article shows, these costs also translate into avoidable deaths from a treatable illness.

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Sarah E Wakeman, *Josiah D Rich Massachusetts General Hospital Substance Use Disorder Initiative, Harvard Medical School, Boston, MA, USA (SEW); and The Center for Prisoner Health and Human Rights at the Miriam Hospital, Brown University, Providence, RI 02906, USA [email protected] JDR was supported by NIH grants K24DA022112 and P30AI42853. JDR is a stockholder in Alkermes. SEW declares no competing interests. Copyright © Wakeman et al. Open access article distributed under the terms of CC BY-NC-ND. 1

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UNODC, ILO, UNDP, WHO, UNAIDS. HIV prevention, treatment and care in prisons and other closed settings: A comprehensive package of interventions. Vienna: United Nations Office of Drugs and Crime, 2013. Pew Center on the States. One in 31: the long reach of American corrections. Washington: The Pew Charitable Trusts, 2009. Binswanger IA, Stern MF, Deyo RA, et al. Release from prison—a high risk of death for former inmates. N Engl J Med 2007; 356: 157–65. Bewley-Taylor D HC, Allen R. The incarceration of drug offenders: an overview. London: The Beckley Foundation Drug Policy Programme, 2009.

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CASA: Behind Bars II: Substance abuse and America’s prison population. New York: National Center on Addiction and Substance Abuse at Columbia University, 2010. Tomasino V, Swanson AJ, Nolan J, Shuman HI. The Key Extended Entry Program (KEEP): a methadone treatment program for opiate-dependent inmates. Mt Sinai J Med 2001; 68: 14–20. Gordon MS, Kinlock TW, Schwartz RP, O’Grady KE. A randomized clinical trial of methadone maintenance for prisoners: findings at 6 months post-release. Addiction 2008; 103: 1333–42. Schwartz RP, Gryczynski J, O’Grady KE, et al. Opioid agonist treatments and heroin overdose deaths in Baltimore, Maryland, 1995–2009. Am J Public Health 2013; 103: 917–22. Rich JD, Boutwell AE, Shield DC, et al. Attitudes and practices regarding the use of methadone in US state and federal prisons. J Urban Health 2005; 82: 411–19. Chang Z, Lichtenstein P, Larsson H, Fazel S. Substance use disorders, psychiatric disorders, and mortality after release from prison: a nationwide longitudinal cohort study. Lancet Psychiatry 2015; published online April 22. http://dx.doi.org/10.1016/S2215-0366(15)00088-7. WHO. Guidelines for the psychosocially assisted pharmacological treatment of opioid dependence. Geneva: World Health Organization, 2009. Allen SA, Wakeman SE, Cohen RL, Rich JD. Physicians in US prisons in the era of mass incarceration. Int J Prison Health 2010; 6: 100–06. Mumola CJ, Karberg JC. Drug use and dependence, state and federal prisoners, 2004. Washington: Bureau of Justice Statistics, 2006. Rich JD, McKenzie M, Larney S, et al. Methadone continuation versus forced withdrawal on incarceration in a US prison: a randomised, open-label, trial. Lancet (in press).

True parity in North American psychiatry

Bruno Ehrs/Corbis

There is no health without mental health. This will be one of my themes when I assume the role of president of the American Psychiatric Association (APA) in May, 2015. The passage of the Mental Health Parity and Addiction Equity Act in 2008 and of the Affordable Care Act in 2010 provides Americans with the largest

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expansion of health coverage for mental health and substance use disorders in a generation.1 This means that treatment for conditions such as anxiety, depression, and post-traumatic stress disorder (PTSD) are now considered essential health benefits. However, many barriers remain in the quest to obtain true parity for our patients who have mental health and substance use disorders. One of the primary barriers is the stigma associated with mental illness and substance misuse.2 Studies show that 25% of all US adults, about 61·5 million Americans, have a mental disorder in a given year.3 Nevertheless, many members of the public are reluctant to admit that these statistics apply to them or their family members because of the stigma attached to having a mental illness. Even when mental health services are available, stigma can lead to reluctance to seek treatment. Another barrier to obtaining mental health care is the fragmentation of mental health and other medical services in the USA. 4 The APA is advocating new models of delivery of mental health care in www.thelancet.com/psychiatry Vol 2 May 2015

Substance use disorders and avoidable mortality after prison.

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