37
Ranolazine and atrial fibrillation in NSTEACS
21. Fragakis N, Koskinas KC, Katritsis DG, Pagourelias ED, Zografos T, Geleris P. Comparison of effectiveness of ranolazine plus amiodarone versus amiodarone alone for conversion of recent-onset atrial fibrillation. Am J Cardiol 2012;110:673 –7. 22. Koskinas KC, Fragakis N, Katritsis D, Skeberis V, Vassilikos V. Ranolazine enhances the efficacy of amiodarone for conversion of recent-onset atrial fibrillation. Europace 2014;16:973 –9. 23. Murdock DK, Kaliebe J, Larrain G. The use of ranolazine to facilitate electrical cardioversion in cardioversion-resistant patients: a case series. Pacing Clin Electrophysiol 2012;35:302 –7. 24. The HARMONY Study. 2014. http://www.gilead.com/news/press-releases/2014/5/ gilead-announces-results-from-phase-2-study-showing-reduction-in-atrial-fibrillation-
burden-with-the-investigational-combination-of-ranolazine-and-lowdose-droneda rone (19 June 2014, date last accessed). 25. Ranolazine in Atrial Fibrillation Following An ELectricaL CardiOversion (RAFAELO). http://ClinicalTrials.gov/show/NCT01534962 (14 June 2014, date last accessed). 26. Randomized Double Blind Control Trial on Effects of Ranolazine on New Onset Atrial Fibrillation. http://ClinicalTrials.gov/show/NCT01590979 (14 June 2014, date last accessed). 27. Suppression Of Atrial Fibrillation With Ranolazine After Cardiac Surgery. http://ClinicalTrials.gov/show/NCT01352416 (14 June 2014, date last accessed).
EP CASE EXPRESS
doi:10.1093/europace/euu021 Online publish-ahead-of-print 7 July 2014
.............................................................................................................................................................................
Superior vena cava syndrome after radiofrequency sinus node modification treated with thrombolysis and stent implantation A. Marciniak*, M. Gonsalves, and M. M. Gallagher Departments of Cardiology and Radiology, St. George’s Hospital, London SW17 0QT, UK
* Corresponding author. Tel: +44 208 725 3079; fax: +44 20 8725 4117. E-mail address: [email protected]
The full-length version of this report can be viewed at: http://www.escardio.org/communities/EHRA/publications/ep-case-reports/ Documents/Superior-vena-cava-syndrome.pdf. Published on behalf of the European Society of Cardiology. All rights reserved. & The Author 2014. For permissions please email: [email protected].
Downloaded from by guest on November 16, 2015
A 30-year-old woman was admitted with symptomatic bradycardia 2 weeks after undergoing a third ablation procedure for inappropriate sinus tachycardia (IST) in another centre. A permanent pacemaker was implanted. She re-presented 3 days later with swelling of both arms, neck and head consistent with superior venae cava (SVC) obstruction syndrome. Venography showed bilateral brachiocephalic vein thrombosis extending to the SVC. There was no symptomatic improvement with therapeutic anticoagulation and repeat venography demonstrated increased thrombus load. Systemic thrombolysis was performed and subsequent venography confirmed the resolution of the thrombus but persistent SVC obstruction (Figure A). A combined procedure was performed to stent the SVC and to revise the pacing system. The atrial lead was removed and the ventricular lead was withdrawn into the subclavian vein providing access to the left subclavian vein and a channel through the occlusion. Via a right femoral approach the SVC obstruction was stented with self-expanding stents (Figure B). A new atrial lead was inserted and the existing RV lead was advanced through the SVC stent and positioned in the right atrium and RV septum, respectively. This procedure resulted in a complete resolution of the symptoms within 12 h. Warfarin was restarted and the patient was discharged.
Ranolazine and atrial fibrillation in NSTEACS
21. Fragakis N, Koskinas KC, Katritsis DG, Pagourelias ED, Zografos T, Geleris P. Comparison of effectiveness of ranolazine plus amiodarone versus amiodarone alone for conversion of recent-onset atrial fibrillation. Am J Cardiol 2012;110:673 –7. 22. Koskinas KC, Fragakis N, Katritsis D, Skeberis V, Vassilikos V. Ranolazine enhances the efficacy of amiodarone for conversion of recent-onset atrial fibrillation. Europace 2014;16:973 –9. 23. Murdock DK, Kaliebe J, Larrain G. The use of ranolazine to facilitate electrical cardioversion in cardioversion-resistant patients: a case series. Pacing Clin Electrophysiol 2012;35:302 –7. 24. The HARMONY Study. 2014. http://www.gilead.com/news/press-releases/2014/5/ gilead-announces-results-from-phase-2-study-showing-reduction-in-atrial-fibrillation-
burden-with-the-investigational-combination-of-ranolazine-and-lowdose-droneda rone (19 June 2014, date last accessed). 25. Ranolazine in Atrial Fibrillation Following An ELectricaL CardiOversion (RAFAELO). http://ClinicalTrials.gov/show/NCT01534962 (14 June 2014, date last accessed). 26. Randomized Double Blind Control Trial on Effects of Ranolazine on New Onset Atrial Fibrillation. http://ClinicalTrials.gov/show/NCT01590979 (14 June 2014, date last accessed). 27. Suppression Of Atrial Fibrillation With Ranolazine After Cardiac Surgery. http://ClinicalTrials.gov/show/NCT01352416 (14 June 2014, date last accessed).
EP CASE EXPRESS
doi:10.1093/europace/euu021 Online publish-ahead-of-print 7 July 2014
.............................................................................................................................................................................
Superior vena cava syndrome after radiofrequency sinus node modification treated with thrombolysis and stent implantation A. Marciniak*, M. Gonsalves, and M. M. Gallagher Departments of Cardiology and Radiology, St. George’s Hospital, London SW17 0QT, UK
* Corresponding author. Tel: +44 208 725 3079; fax: +44 20 8725 4117. E-mail address: [email protected]
The full-length version of this report can be viewed at: http://www.escardio.org/communities/EHRA/publications/ep-case-reports/ Documents/Superior-vena-cava-syndrome.pdf. Published on behalf of the European Society of Cardiology. All rights reserved. & The Author 2014. For permissions please email: [email protected].
Downloaded from by guest on November 16, 2015
A 30-year-old woman was admitted with symptomatic bradycardia 2 weeks after undergoing a third ablation procedure for inappropriate sinus tachycardia (IST) in another centre. A permanent pacemaker was implanted. She re-presented 3 days later with swelling of both arms, neck and head consistent with superior venae cava (SVC) obstruction syndrome. Venography showed bilateral brachiocephalic vein thrombosis extending to the SVC. There was no symptomatic improvement with therapeutic anticoagulation and repeat venography demonstrated increased thrombus load. Systemic thrombolysis was performed and subsequent venography confirmed the resolution of the thrombus but persistent SVC obstruction (Figure A). A combined procedure was performed to stent the SVC and to revise the pacing system. The atrial lead was removed and the ventricular lead was withdrawn into the subclavian vein providing access to the left subclavian vein and a channel through the occlusion. Via a right femoral approach the SVC obstruction was stented with self-expanding stents (Figure B). A new atrial lead was inserted and the existing RV lead was advanced through the SVC stent and positioned in the right atrium and RV septum, respectively. This procedure resulted in a complete resolution of the symptoms within 12 h. Warfarin was restarted and the patient was discharged.
