ChemInform 1990, 21, No. 31, Abstract 303

ChemInform 1990, 21, No. 31, Abstract 303

ChemInform Abstract Condensation of the silyl derivative of the imidazole (II) with the component (I) for a short time gives regioselectively the nucleoside (V) which is converted to the title compound (VI). A regiomer of (V), however, is obtained when a longer reaction time is used. Similarly, the compounds (VII) and (VIII) are prepared. The title compound (XI) is obtainable from the known precursor (IX).

Synthesis of nucleosides as potential inhibitors of purine biosynthesis.

The synthesis of analogues of 4-carboxy-5-amino-1-beta-D-ribofuranosylimidazole-5'-phosphate (CAIR) in which the carbonyl group is replaced by a group...
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