Accepted Manuscript The Addition of Hemi-arch Replacement to Aortic Root Surgery Does Not Affect Safety S.C. Malaisrie, MD, B. Duncan, MD, C.K. Mehta, MD, M.V. Badiwala, MD, D. Rinewalt, MD, J. Kruse, RN, BSN, Z. Li, MS, A.-C. Andrei, PhD, P.M. McCarthy, MD PII:
S0022-5223(15)00433-X
DOI:
10.1016/j.jtcvs.2015.03.020
Reference:
YMTC 9448
To appear in:
The Journal of Thoracic and Cardiovascular Surgery
Received Date: 22 December 2014 Revised Date:
27 February 2015
Accepted Date: 15 March 2015
Please cite this article as: Malaisrie SC, Duncan B, Mehta CK, Badiwala MV, Rinewalt D, Kruse J, Li Z, Andrei A-C, McCarthy PM, The Addition of Hemi-arch Replacement to Aortic Root Surgery Does Not Affect Safety, The Journal of Thoracic and Cardiovascular Surgery (2015), doi: 10.1016/ j.jtcvs.2015.03.020. This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.
ACCEPTED MANUSCRIPT
The Addition of Hemi-arch Replacement to Aortic Root Surgery Does Not Affect Safety S. C. Malaisrie, MD1, B. Duncan, MD1, C. K. Mehta, MD1, M. V. Badiwala, MD1, D. Rinewalt, MD1, J. Kruse RN, BSN2, Z. Li, MS2, A.-C. Andrei, PhD2, P. M. McCarthy, MD1. Division of Cardiothoracic Surgery, Northwestern University, Chicago, IL, 2Bluhm Cardiovascular Institute, Northwestern Medicine, Chicago, IL
Presented at the AATS Aortic Symposium 2014
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1
SC
Key Words: Aortic root replacement, hemi-arch, aortic aneurysm, Bentall
M AN U
Funding Sources: None
Disclosures: None
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Corresponding Author S. Chris Malaisrie, MD Associate Professor of Surgery at Northwestern University Feinberg School of Medicine Division of Cardiac Surgery Bluhm Cardiovascular Institute 201 East Huron Street, Suite 11-140 Chicago, IL 60611-2908 Telephone: Office - (312) 695-2517 Mobile - (312) 912-1522 Fax: (312) 695-1903 E-mail: [email protected]
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Manuscript Word Count: 2907 (limit 3500)
Page 1 of 25
ACCEPTED MANUSCRIPT
Abstract
Objective: A hemi-arch reconstruction, using deep hypothermic circulatory arrest, is the
RI PT
conventional approach for proximal aortic arch reconstruction but carries risks of neurologic events and coagulopathy. The addition of a hemi-arch reconstruction to an aortic root
replacement may prevent future aortic arch pathology. Outcomes of this approach at a tertiary care institution were examined to determine whether the addition of a hemi-arch reconstruction
SC
to an aortic root replacement conferred any additional risk.
M AN U
Methods: 384 patients underwent an aortic root replacement between April 2004 and June 2012. Of them, 177 (46%) had hemi-arch replacement. Propensity score-matching yielded 133 pairs of hemi-arch and non-hemi-arch patients.
Results: Sinus segment diameter was similar between groups; ascending aortic diameter was
TE D
greater in the hemi-arch group (median 50 vs. 44 mm; p
S0022-5223(15)00433-X
DOI:
10.1016/j.jtcvs.2015.03.020
Reference:
YMTC 9448
To appear in:
The Journal of Thoracic and Cardiovascular Surgery
Received Date: 22 December 2014 Revised Date:
27 February 2015
Accepted Date: 15 March 2015
Please cite this article as: Malaisrie SC, Duncan B, Mehta CK, Badiwala MV, Rinewalt D, Kruse J, Li Z, Andrei A-C, McCarthy PM, The Addition of Hemi-arch Replacement to Aortic Root Surgery Does Not Affect Safety, The Journal of Thoracic and Cardiovascular Surgery (2015), doi: 10.1016/ j.jtcvs.2015.03.020. This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.
ACCEPTED MANUSCRIPT
The Addition of Hemi-arch Replacement to Aortic Root Surgery Does Not Affect Safety S. C. Malaisrie, MD1, B. Duncan, MD1, C. K. Mehta, MD1, M. V. Badiwala, MD1, D. Rinewalt, MD1, J. Kruse RN, BSN2, Z. Li, MS2, A.-C. Andrei, PhD2, P. M. McCarthy, MD1. Division of Cardiothoracic Surgery, Northwestern University, Chicago, IL, 2Bluhm Cardiovascular Institute, Northwestern Medicine, Chicago, IL
Presented at the AATS Aortic Symposium 2014
RI PT
1
SC
Key Words: Aortic root replacement, hemi-arch, aortic aneurysm, Bentall
M AN U
Funding Sources: None
Disclosures: None
EP
TE D
Corresponding Author S. Chris Malaisrie, MD Associate Professor of Surgery at Northwestern University Feinberg School of Medicine Division of Cardiac Surgery Bluhm Cardiovascular Institute 201 East Huron Street, Suite 11-140 Chicago, IL 60611-2908 Telephone: Office - (312) 695-2517 Mobile - (312) 912-1522 Fax: (312) 695-1903 E-mail: [email protected]
AC C
Manuscript Word Count: 2907 (limit 3500)
Page 1 of 25
ACCEPTED MANUSCRIPT
Abstract
Objective: A hemi-arch reconstruction, using deep hypothermic circulatory arrest, is the
RI PT
conventional approach for proximal aortic arch reconstruction but carries risks of neurologic events and coagulopathy. The addition of a hemi-arch reconstruction to an aortic root
replacement may prevent future aortic arch pathology. Outcomes of this approach at a tertiary care institution were examined to determine whether the addition of a hemi-arch reconstruction
SC
to an aortic root replacement conferred any additional risk.
M AN U
Methods: 384 patients underwent an aortic root replacement between April 2004 and June 2012. Of them, 177 (46%) had hemi-arch replacement. Propensity score-matching yielded 133 pairs of hemi-arch and non-hemi-arch patients.
Results: Sinus segment diameter was similar between groups; ascending aortic diameter was
TE D
greater in the hemi-arch group (median 50 vs. 44 mm; p
