RESEARCH ARTICLE

The Clinical Characteristics and Predictors of Refractory Mycoplasma pneumoniae Pneumonia in Children Yuanyuan Zhang, Yunlian Zhou, Shuxian Li, Dehua Yang, Xiling Wu, Zhimin Chen* Department of Pulmonology, Children’s Hospital, Zhejiang University School of Medicine, Hangzhou, P.R. China * [email protected]

Abstract a11111

Objective To analyze the clinical characteristics of refracory Mycoplasma pneumoniae pneumonia (RMPP), and explore the related factors predicting RMPP.

Methods OPEN ACCESS Citation: Zhang Y, Zhou Y, Li S, Yang D, Wu X, Chen Z (2016) The Clinical Characteristics and Predictors of Refractory Mycoplasma pneumoniae Pneumonia in Children. PLoS ONE 11(5): e0156465. doi:10.1371/journal.pone.0156465 Editor: Aldo Scarpa, University of Verona, ITALY Received: November 19, 2015 Accepted: May 13, 2016 Published: May 26, 2016 Copyright: © 2016 Zhang et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Data Availability Statement: All relevant data are within the paper. Funding: This work was supported by grants from National Natural Science Foundation (81200022, 81401301, 81501374). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. Competing Interests: The authors have declared that no competing interests exist.

Retrospective analysis was performed on 634 children with Mycoplasma pneumoniae pneumonia (MPP) hospitalized in our hospital between January 1, 2011 and December 31, 2014. The clinical features, laboratory data, radiological findings between the RMPP group and the general Mycoplasma pneumoniae pneumonia (GMPP) group were compared and the predictive values of related factors were analyzed.

Results The median age of the RMPP patients (n = 145) was much older than that of the GMPP patients (n = 489) (P

The Clinical Characteristics and Predictors of Refractory Mycoplasma pneumoniae Pneumonia in Children.

To analyze the clinical characteristics of refracory Mycoplasma pneumoniae pneumonia (RMPP), and explore the related factors predicting RMPP...
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