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The Effects of Acute Moderate Exercise on Lymphocyte Function and Serum Immunoglobulin Levels S. L. Nehisen-Cannarella, D. C. Nieman, J. Jessen, L. Chang, G. Gusewitch, G. G. B/tx, E. Ashley Department of Health Science, School of Public Health, Loma Linda University. Immunology Center and Center for Health Promotion, Loma Linda University Medical Center

S. L. Nehisen-Cannarella, D. C. Nieman, J. Jessen, L. Chang, G. Gusewitch, G. G. Blix, andE. Ashley, The

Effects of Acute Moderate Exercise on Lymphocyte Function and Serum Immunoglobulin Levels. mt J Sports Med, Vol 12,No4,pp391—398, 1991. Accepted after revision: September 28, 1990

The extent and duration of changes on lymphocyte function and serum immunoglobulin (Ig) levels were examined in 12 women who walked 45 mm at 60% VO2max in a

laboratory setting. A 2-factor, 2 x 6 design with repeated measures on both factors was utilized. The first factor was condition (exercise and rest), and the second factor was time (six times of measurement over a 24-h period), with treatment order counterbalanced. The 45-mm walk, in comparison to rest in a seated position, was not associated with significant changes in circulating numbers of interleukin-2-activated T cells (CD5 and CD25) or on spontaneous or concanavalin-Astimulated lymphocyte proliferation. A trend for decreased phytohemagglutinin-stimulated lymphocyte proliferation in

Introduction

Brisk walking for exercise is now one of the fastest growing activities in the United States (30). Walking, a low- to moderate-intensity physical activity, has been found to have a higher compliance rate than other activities, because it can easily be incorporated into a busy time schedule, does not require any special skills, equipment, or facility, is convivial, and is much less apt to cause injuries.

comparison to the rest condition, however, was seen 1.5 h following the exercise bout (p = 0.047). The patterns of change

for serum IgG, IgA, and 1gM were significantly different (p=O.OOI, p

The effects of acute moderate exercise on lymphocyte function and serum immunoglobulin levels.

The extent and duration of changes on lymphocyte function and serum immunoglobulin (Ig) levels were examined in 12 women who walked 45 min at 60% VO2 ...
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