THE MECHANISM OF INHIBITION OF B A C T E R I O P H A G E T7 R N A SYNTHESIS BY ACRIDINES, DIACRIDINES AND ACTINOMYCIN D
ANDREAS H. SARRIS, EDWARD G. NILES * and E.S. CANELLAKIS
Department of Pharmacology, Yale University, Medical School, New Haven, Conn. 06510 (U.S.A.) (Received May 10th, 1976)
Summary A homologous series of diacridines, as well as 9-amino acridine, were assayed for their ability to interfere with the synthesis of R N A (bands I--VI) by bacteriophage T7 DNA