www.nature.com/scientificreports
OPEN
received: 25 October 2016 accepted: 24 January 2017 Published: 10 March 2017
The need for strengthening the influenza virus detection ability of hospital clinical laboratories: an investigation of the 2009 pandemic Shigui Yang1, Yuqing Zhou1, Yuanxia Cui1, Cheng Ding1, Jie Wu1, Min Deng1, Chencheng Wang1, Xiaoqing Lu1, Xiaoxiao Chen1, Yiping Li2, Dongyan Shi1, Fenfang Mi3 & Lanjuan Li1 Most hospital clinical laboratories (HCLs) in China are unable to perform influenza virus detection. It remains unclear whether the influenza detection ability of HCLs influences the early identification and mortality rate of influenza. A total of 739 hospitalized patients with 2009 influenza A (H1N1) virus treated at 65 hospitals between May and December, 2009, in Zhejiang, China, were included based on identifications by HCLs and by public health laboratories (PHLs) of the Centers for Disease Control and Prevention. Of the patients, 407 (55.1%) were male, 17 died, resulting in an in-hospital mortality rate of 2.3%, and 297 patients were identified by HCLs and 442 by PHLs. The results indicated that a 24hour delay in identification led to a 13% increase in the odds of death (OR = 1.13, P
OPEN
received: 25 October 2016 accepted: 24 January 2017 Published: 10 March 2017
The need for strengthening the influenza virus detection ability of hospital clinical laboratories: an investigation of the 2009 pandemic Shigui Yang1, Yuqing Zhou1, Yuanxia Cui1, Cheng Ding1, Jie Wu1, Min Deng1, Chencheng Wang1, Xiaoqing Lu1, Xiaoxiao Chen1, Yiping Li2, Dongyan Shi1, Fenfang Mi3 & Lanjuan Li1 Most hospital clinical laboratories (HCLs) in China are unable to perform influenza virus detection. It remains unclear whether the influenza detection ability of HCLs influences the early identification and mortality rate of influenza. A total of 739 hospitalized patients with 2009 influenza A (H1N1) virus treated at 65 hospitals between May and December, 2009, in Zhejiang, China, were included based on identifications by HCLs and by public health laboratories (PHLs) of the Centers for Disease Control and Prevention. Of the patients, 407 (55.1%) were male, 17 died, resulting in an in-hospital mortality rate of 2.3%, and 297 patients were identified by HCLs and 442 by PHLs. The results indicated that a 24hour delay in identification led to a 13% increase in the odds of death (OR = 1.13, P
