ORL 2015;77:109–116 DOI: 10.1159/000375534 Received: August 18, 2014 Accepted: January 26, 2015 Published online: April 15, 2015
© 2015 S. Karger AG, Basel 0301–1569/15/0772–0109$39.50/0 www.karger.com/orl
Original Paper
The Neutrophil-to-Lymphocyte Ratio Correlates with Age in Patients with Papillary Thyroid Carcinoma Jifeng Liu a Jintao Du b Jinchuan Fan a Kun Liu a Bing Zhang a Shaoxin Wang a Wei Wang a Zhaohui Wang a Yongcong Cai a Chunhua Li a Tao Yu a Guiquan Zhu a Jin Chen a Chao Li a a
Department of Head and Neck Surgery, Sichuan Cancer Hospital, and b Department of Otorhinolaryngology – Head and Neck Surgery, West China Hospital of Sichuan University, Chengdu, China
Key Words Neutrophil-to-lymphocyte ratio · Papillary thyroid carcinoma · Age · Leukocytes · Thyrotropin Abstract Aim: The aim of this study is to explore the relationship between the neutrophil-to-lymphocyte ratio (NLR) and clinicopathological features in patients with papillary thyroid carcinoma (PTC). Methods: We performed an analysis of 843 patients, including 321 patients with PTC, 83 patients with thyroid adenoma and 439 patients with nodular goiter (NG). Thyroglobulin and thyrotropin were measured in each patient. Neutrophils, lymphocytes, and platelets were counted. Statistical analysis was used to correlate the NLR with demographic and histopathologic characteristics of the patients. Result: Age correlated with NLR and lymphocyte number in patients with PTC and NG. In patients aged >45 years, those with PTC had a higher NLR and a lower lymphocyte count than those with NG. Patients with PTC aged
© 2015 S. Karger AG, Basel 0301–1569/15/0772–0109$39.50/0 www.karger.com/orl
Original Paper
The Neutrophil-to-Lymphocyte Ratio Correlates with Age in Patients with Papillary Thyroid Carcinoma Jifeng Liu a Jintao Du b Jinchuan Fan a Kun Liu a Bing Zhang a Shaoxin Wang a Wei Wang a Zhaohui Wang a Yongcong Cai a Chunhua Li a Tao Yu a Guiquan Zhu a Jin Chen a Chao Li a a
Department of Head and Neck Surgery, Sichuan Cancer Hospital, and b Department of Otorhinolaryngology – Head and Neck Surgery, West China Hospital of Sichuan University, Chengdu, China
Key Words Neutrophil-to-lymphocyte ratio · Papillary thyroid carcinoma · Age · Leukocytes · Thyrotropin Abstract Aim: The aim of this study is to explore the relationship between the neutrophil-to-lymphocyte ratio (NLR) and clinicopathological features in patients with papillary thyroid carcinoma (PTC). Methods: We performed an analysis of 843 patients, including 321 patients with PTC, 83 patients with thyroid adenoma and 439 patients with nodular goiter (NG). Thyroglobulin and thyrotropin were measured in each patient. Neutrophils, lymphocytes, and platelets were counted. Statistical analysis was used to correlate the NLR with demographic and histopathologic characteristics of the patients. Result: Age correlated with NLR and lymphocyte number in patients with PTC and NG. In patients aged >45 years, those with PTC had a higher NLR and a lower lymphocyte count than those with NG. Patients with PTC aged
