Case Study
Thoracic liposarcoma: Resection and chest wall reconstruction
Asian Cardiovascular & Thoracic Annals 2014, Vol. 22(9) 1112–1115 ß The Author(s) 2013 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav DOI: 10.1177/0218492313504578 aan.sagepub.com
Gerardo Andre´s Obeso Carillo1, Montserrat Blanco Ramos1, Gonzalo De Castro Parga2, Eva Marı´a Garcia Fontan1 and Miguel Angel Can˜izares Carretero1
Abstract Liposarcoma is a malignant neoplasm of mesodermal origin derived from adipose tissue. It most often originates in the extremities and retroperitoneum, and less frequently in the head and neck. Liposarcoma involving the chest wall is extremely rare with few reported cases. Surgery is the mainstay of treatment, and complete resection is the major factor influencing survival. We describe the case of a 65-year-old man diagnosed with a dedifferentiated liposarcoma of the chest wall, who underwent radical resection and chest wall reconstruction with a latissimus dorsi musculocutaneous flap.
Keywords Liposarcoma, soft tissue neoplasms, thoracic wall
Introduction Liposarcoma is a malignant neoplasm of mesodermal origin, derived from adipose tissue, which arises from primitive mesenchymal cells deep in soft tissue such as intermuscular fascial planes and similar deep-seated vascular structures.1 It is usually located in the extremities, particularly the thigh and retroperitoneum. Liposarcoma involving the chest wall is extremely rare, and only a few cases have been reported.2,3
Case report A 65-year-old man was referred to our institution for evaluation of a chest wall mass. He was dyslipidemic, a chronic carrier of hepatitis C virus, and had undergone an emergency splenectomy following a road traffic accident. Physical examination showed a soft and very painful palpable mass on the right lateral chest wall, which had increased considerably over the previous 7 months. Laboratory results were normal except for hypercholesterolemia, which had been recorded previously. Computed tomography revealed a 7.4 6-cm well-defined mass in the soft tissue of the right chest wall, located between the serratus anterior and intercostal muscles (Figure 1a). The tumor was in contact with the 8th and 9th ribs, without bone involvement. There were also multiple small (
Thoracic liposarcoma: Resection and chest wall reconstruction
Asian Cardiovascular & Thoracic Annals 2014, Vol. 22(9) 1112–1115 ß The Author(s) 2013 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav DOI: 10.1177/0218492313504578 aan.sagepub.com
Gerardo Andre´s Obeso Carillo1, Montserrat Blanco Ramos1, Gonzalo De Castro Parga2, Eva Marı´a Garcia Fontan1 and Miguel Angel Can˜izares Carretero1
Abstract Liposarcoma is a malignant neoplasm of mesodermal origin derived from adipose tissue. It most often originates in the extremities and retroperitoneum, and less frequently in the head and neck. Liposarcoma involving the chest wall is extremely rare with few reported cases. Surgery is the mainstay of treatment, and complete resection is the major factor influencing survival. We describe the case of a 65-year-old man diagnosed with a dedifferentiated liposarcoma of the chest wall, who underwent radical resection and chest wall reconstruction with a latissimus dorsi musculocutaneous flap.
Keywords Liposarcoma, soft tissue neoplasms, thoracic wall
Introduction Liposarcoma is a malignant neoplasm of mesodermal origin, derived from adipose tissue, which arises from primitive mesenchymal cells deep in soft tissue such as intermuscular fascial planes and similar deep-seated vascular structures.1 It is usually located in the extremities, particularly the thigh and retroperitoneum. Liposarcoma involving the chest wall is extremely rare, and only a few cases have been reported.2,3
Case report A 65-year-old man was referred to our institution for evaluation of a chest wall mass. He was dyslipidemic, a chronic carrier of hepatitis C virus, and had undergone an emergency splenectomy following a road traffic accident. Physical examination showed a soft and very painful palpable mass on the right lateral chest wall, which had increased considerably over the previous 7 months. Laboratory results were normal except for hypercholesterolemia, which had been recorded previously. Computed tomography revealed a 7.4 6-cm well-defined mass in the soft tissue of the right chest wall, located between the serratus anterior and intercostal muscles (Figure 1a). The tumor was in contact with the 8th and 9th ribs, without bone involvement. There were also multiple small (
