Perfusion
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Tissue perfusion in neonates undergoing open-heart surgery using autologous umbilical cord blood or donor blood components K Chasovskyi, O Fedevych, DM McMullan, Y Mykychak, G Vorobiova, V Zhovnir and I Yemets Perfusion published online 23 September 2014 DOI: 10.1177/0267659114550234 The online version of this article can be found at: http://prf.sagepub.com/content/early/2014/09/19/0267659114550234
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550234 research-article2014
PRF0010.1177/0267659114550234PerfusionChasovskyi et al.
Original paper
Tissue perfusion in neonates undergoing open-heart surgery using autologous umbilical cord blood or donor blood components
Perfusion 1–8 © The Author(s) 2014 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav DOI: 10.1177/0267659114550234 prf.sagepub.com
K Chasovskyi,1 O Fedevych,2 DM McMullan,3 Y Mykychak,2 G Vorobiova,4 V Zhovnir5 and I Yemets2
Abstract Background: This study evaluates the hemoglobin-oxygen relationship and tissue perfusion during cardiopulmonary bypass (CPB) in neonates undergoing open-heart surgery using autologous umbilical cord blood or donor blood components. Methods: We compared perioperative hematocrit (Hct), fetal hemoglobin (HbF), p50O2, pH, pCO2, serum lactate, duration of mechanical ventilation and intensive care unit (ICU) length of stay in neonates undergoing open-heart surgery using autologous umbilical cord blood (Group I, N=45) or donor blood components (Group II, N=65). The groups were similar with respect to diagnosis, weight, type of procedure, duration of CPB and duration of myocardial ischemia. Results: Mean p50O2 was significantly lower in Group I during CPB (19.7 vs. 22.3 mmHg, p=0.004) and at the end of CPB (20.1 vs. 22.8 mmHg, p=0.003). Median peak lactate during CPB was higher in Group I (4.8 vs. 2.2 mmol/l, p
http://prf.sagepub.com/
Tissue perfusion in neonates undergoing open-heart surgery using autologous umbilical cord blood or donor blood components K Chasovskyi, O Fedevych, DM McMullan, Y Mykychak, G Vorobiova, V Zhovnir and I Yemets Perfusion published online 23 September 2014 DOI: 10.1177/0267659114550234 The online version of this article can be found at: http://prf.sagepub.com/content/early/2014/09/19/0267659114550234
Published by: http://www.sagepublications.com
Additional services and information for Perfusion can be found at: Email Alerts: http://prf.sagepub.com/cgi/alerts Subscriptions: http://prf.sagepub.com/subscriptions Reprints: http://www.sagepub.com/journalsReprints.nav Permissions: http://www.sagepub.com/journalsPermissions.nav
>> OnlineFirst Version of Record - Sep 23, 2014 What is This?
Downloaded from prf.sagepub.com at TEXAS SOUTHERN UNIVERSITY on November 27, 2014
550234 research-article2014
PRF0010.1177/0267659114550234PerfusionChasovskyi et al.
Original paper
Tissue perfusion in neonates undergoing open-heart surgery using autologous umbilical cord blood or donor blood components
Perfusion 1–8 © The Author(s) 2014 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav DOI: 10.1177/0267659114550234 prf.sagepub.com
K Chasovskyi,1 O Fedevych,2 DM McMullan,3 Y Mykychak,2 G Vorobiova,4 V Zhovnir5 and I Yemets2
Abstract Background: This study evaluates the hemoglobin-oxygen relationship and tissue perfusion during cardiopulmonary bypass (CPB) in neonates undergoing open-heart surgery using autologous umbilical cord blood or donor blood components. Methods: We compared perioperative hematocrit (Hct), fetal hemoglobin (HbF), p50O2, pH, pCO2, serum lactate, duration of mechanical ventilation and intensive care unit (ICU) length of stay in neonates undergoing open-heart surgery using autologous umbilical cord blood (Group I, N=45) or donor blood components (Group II, N=65). The groups were similar with respect to diagnosis, weight, type of procedure, duration of CPB and duration of myocardial ischemia. Results: Mean p50O2 was significantly lower in Group I during CPB (19.7 vs. 22.3 mmHg, p=0.004) and at the end of CPB (20.1 vs. 22.8 mmHg, p=0.003). Median peak lactate during CPB was higher in Group I (4.8 vs. 2.2 mmol/l, p
