Letters
Tobacco Use and Oral HPV-16 Infection
associations between objective biomarkers reflective of all current tobacco exposures (environmental, smoking, and use of smokeless tobacco) and oral HPV-16 prevalence.
Oral human papillomavirus type 16 (HPV-16), a sexually transmitted infection, is believed to be responsible for the increase in incidence of oropharyngeal squamous cell cancers in the United States.1 An association between selfreported number of cigarettes currently smoked per day and oral HPV prevalence has been observed.2,3 We investigated
Methods | The National Health and Nutrition Examination Survey (NHANES) is a cross-sectional, stratified multistage probability sample of the US population.4 The NHANES was approved by the National Center for Health Statistics institutional review board and written informed consent was
RESEARCH LETTER
Table 1. Description of NHANES Study Population Included in Analysis by Current Self-reported Tobacco Usea Tobacco Overall (N = 6887)
Current Use (n = 2012)
No Current Use (n = 4875)
Male
3494 (51.2)
1240 (61.4)
2254 (47.2)
Female
3393 (48.8)
772 (38.6)
2621 (52.8)
18-29
2219 (29.2)
685 (32.5)
1534 (27.9)
30-39
1551 (21.9)
454 (20.9)
1097 (22.3)
40-49
1596 (24.5)
476 (25.4)
1120 (24.1)
50-59
1521 (24.4)
397 (21.2)
1124 (25.6)
Non-Hispanic white
2724 (64.2)
996 (68.3)
1728 (62.6)
Non-Hispanic black
1548 (12.2)
498 (13.8)
1050 (11.5)
Hispanic, other, multiracial
2615 (23.6)
518 (17.8)
2097 (25.9)
Tobacco Use and Oral HPV-16 Infection
associations between objective biomarkers reflective of all current tobacco exposures (environmental, smoking, and use of smokeless tobacco) and oral HPV-16 prevalence.
Oral human papillomavirus type 16 (HPV-16), a sexually transmitted infection, is believed to be responsible for the increase in incidence of oropharyngeal squamous cell cancers in the United States.1 An association between selfreported number of cigarettes currently smoked per day and oral HPV prevalence has been observed.2,3 We investigated
Methods | The National Health and Nutrition Examination Survey (NHANES) is a cross-sectional, stratified multistage probability sample of the US population.4 The NHANES was approved by the National Center for Health Statistics institutional review board and written informed consent was
RESEARCH LETTER
Table 1. Description of NHANES Study Population Included in Analysis by Current Self-reported Tobacco Usea Tobacco Overall (N = 6887)
Current Use (n = 2012)
No Current Use (n = 4875)
Male
3494 (51.2)
1240 (61.4)
2254 (47.2)
Female
3393 (48.8)
772 (38.6)
2621 (52.8)
18-29
2219 (29.2)
685 (32.5)
1534 (27.9)
30-39
1551 (21.9)
454 (20.9)
1097 (22.3)
40-49
1596 (24.5)
476 (25.4)
1120 (24.1)
50-59
1521 (24.4)
397 (21.2)
1124 (25.6)
Non-Hispanic white
2724 (64.2)
996 (68.3)
1728 (62.6)
Non-Hispanic black
1548 (12.2)
498 (13.8)
1050 (11.5)
Hispanic, other, multiracial
2615 (23.6)
518 (17.8)
2097 (25.9)
