European Journal of Cardio-Thoracic Surgery Advance Access published February 3, 2015
ORIGINAL ARTICLE
European Journal of Cardio-Thoracic Surgery (2015) 1–6 doi:10.1093/ejcts/ezu546
Transcatheter mitral valve implantation via transapical approach: an early experience† Lars Sondergaard*, Matthew Brooks, Nikolaj Ihlemann, Anders Jonsson, Susanne Holme, Mariann Tang, Kim Terp and Arshad Quadri Department of Cardiology, Rigshospitalet, Copenhagen, Denmark * Corresponding author. Department of Cardiology, Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen, Denmark. Tel: +45-35452018; fax: +45-35452705; e-mail: [email protected] (L. Sondergaard). Received 21 September 2014; received in revised form 5 December 2014; accepted 11 December 2014
Abstract OBJECTIVES: As many as 50% of patients with severe symptomatic mitral valve regurgitation are denied surgical valve replacement or repair due to high operative risk. We describe an early series of cases of transcatheter implantation with a CardiAQ™ mitral valve via a transapical approach. METHODS: Three consecutive patients with an Society of Thoracic Surgeons (STS) mortality score of >22% were selected for transcatheter mitral valve implantation (TMVI) on compassionate grounds. All patients were elderly, had severe mitral regurgitation (MR), were in Class IV heart failure and deemed unsuitable for the MitraClip. Two of the patients had functional MR in the setting of ischaemic cardiomyopathy with left ventricular ejection fraction (LVEF)
ORIGINAL ARTICLE
European Journal of Cardio-Thoracic Surgery (2015) 1–6 doi:10.1093/ejcts/ezu546
Transcatheter mitral valve implantation via transapical approach: an early experience† Lars Sondergaard*, Matthew Brooks, Nikolaj Ihlemann, Anders Jonsson, Susanne Holme, Mariann Tang, Kim Terp and Arshad Quadri Department of Cardiology, Rigshospitalet, Copenhagen, Denmark * Corresponding author. Department of Cardiology, Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen, Denmark. Tel: +45-35452018; fax: +45-35452705; e-mail: [email protected] (L. Sondergaard). Received 21 September 2014; received in revised form 5 December 2014; accepted 11 December 2014
Abstract OBJECTIVES: As many as 50% of patients with severe symptomatic mitral valve regurgitation are denied surgical valve replacement or repair due to high operative risk. We describe an early series of cases of transcatheter implantation with a CardiAQ™ mitral valve via a transapical approach. METHODS: Three consecutive patients with an Society of Thoracic Surgeons (STS) mortality score of >22% were selected for transcatheter mitral valve implantation (TMVI) on compassionate grounds. All patients were elderly, had severe mitral regurgitation (MR), were in Class IV heart failure and deemed unsuitable for the MitraClip. Two of the patients had functional MR in the setting of ischaemic cardiomyopathy with left ventricular ejection fraction (LVEF)
