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Int J Radiat Oncol Biol Phys. Author manuscript; available in PMC 2016 September 01. Published in final edited form as: Int J Radiat Oncol Biol Phys. 2015 September 1; 93(1): 91–101. doi:10.1016/j.ijrobp.2015.05.010.

Utilization and Outcomes of Breast Brachytherapy in Younger Women

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Grace L Smith, MD, PhD, MPH, Jinhai Huo, PhD, MD, MPH, Sharon H. Giordano, MD, MPH, Kelly K. Hunt, MD, Thomas A Buchholz, MD, and Benjamin D Smith, MD Departments of Radiation Oncology (GLS, TAB, BDS), Health Services Research (GLS, JH, SHG, BDS), Surgical Oncology (KKH) and Breast Medical Oncology (SHG), The University of Texas MD Anderson Cancer Center

Abstract Background—Breast brachytherapy after lumpectomy is controversial in younger patients, as effectiveness is unclear and selection criteria are debated.

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Methods—Using MarketScan® healthcare claims data, we identified 45,884 invasive breast cancer patients (ages 18–64), treated from 2003–2010 with lumpectomy, followed by brachytherapy (n=3,134) or whole breast irradiation (WBI) (n=42,750). We stratified patients into risk groups, based on age (Age

Utilization and Outcomes of Breast Brachytherapy in Younger Women.

To directly compare (1) radiation treatment utilization patterns; (2) risks of subsequent mastectomy; and (3) costs of radiation treatment in patients...
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