HHS Public Access Author manuscript Author Manuscript
Pediatr Pulmonol. Author manuscript; available in PMC 2017 May 08. Published in final edited form as: Pediatr Pulmonol. 2016 December ; 51(12): 1276–1283. doi:10.1002/ppul.23485.
Vitamin D and Pulmonary Function in Obese Asthmatic Children Laura A. Lautenbacher, DO1, Sunit P. Jariwala, MD2, Morri E. Markowitz, MD1, and Deepa Rastogi, MBBS, MS1,* 1Department
of Pediatrics, Children’s Hospital at Montefiore, Albert Einstein College of Medicine, 3415 Bainbridge Ave, Bronx, New York 10467
2Department
Author Manuscript
of Medicine, Montefiore Hospital and Medical Center, Albert Einstein College of Medicine, Bronx, New York
Summary Objective—Asthma-related morbidity is higher among children with vitamin D deficiency and obesity, morbidities that frequently co-exist among minority children. However, the effect of coexistent obesity and vitamin D deficiency on pulmonary function is poorly understood.
Author Manuscript
Methods—We compared percent-predicted values of pulmonary function across vitamin D categories among 72 obese and 71 normal-weight Hispanic and African-American children with asthma recruited at an urban children’s hospital. Serum cytokines associated with Th1 and Th2 inflammation and 25-hydroxyvitamin D (25-OHD) were quantified in fasting serum. 25-OHD levels ≥30 ng/ml were categorized as sufficient,
Pediatr Pulmonol. Author manuscript; available in PMC 2017 May 08. Published in final edited form as: Pediatr Pulmonol. 2016 December ; 51(12): 1276–1283. doi:10.1002/ppul.23485.
Vitamin D and Pulmonary Function in Obese Asthmatic Children Laura A. Lautenbacher, DO1, Sunit P. Jariwala, MD2, Morri E. Markowitz, MD1, and Deepa Rastogi, MBBS, MS1,* 1Department
of Pediatrics, Children’s Hospital at Montefiore, Albert Einstein College of Medicine, 3415 Bainbridge Ave, Bronx, New York 10467
2Department
Author Manuscript
of Medicine, Montefiore Hospital and Medical Center, Albert Einstein College of Medicine, Bronx, New York
Summary Objective—Asthma-related morbidity is higher among children with vitamin D deficiency and obesity, morbidities that frequently co-exist among minority children. However, the effect of coexistent obesity and vitamin D deficiency on pulmonary function is poorly understood.
Author Manuscript
Methods—We compared percent-predicted values of pulmonary function across vitamin D categories among 72 obese and 71 normal-weight Hispanic and African-American children with asthma recruited at an urban children’s hospital. Serum cytokines associated with Th1 and Th2 inflammation and 25-hydroxyvitamin D (25-OHD) were quantified in fasting serum. 25-OHD levels ≥30 ng/ml were categorized as sufficient,
