Supplemental Material can be found at: http://jn.nutrition.org/content/suppl/2015/02/18/jn.114.20828 0.DCSupplemental.html
The Journal of Nutrition Nutritional Epidemiology
Vitamin D Deficiency in School-Age Children Is Associated with Sociodemographic and Lifestyle Factors1–3 Trudy Voortman,4,6,8* Edith H van den Hooven,4,8 Annemieke C Heijboer,7 Albert Hofman,4 Vincent WV Jaddoe,4–6 and Oscar H Franco4 Departments of 4Epidemiology and 5Pediatrics, and 6The Generation R Study Group, Erasmus MC, University Medical Center, Rotterdam, The Netherlands; and 7Department of Clinical Chemistry, VU University Medical Center, Amsterdam, The Netherlands
Background: There is concern about a reemergence of vitamin D deficiency in children in developed countries. Objectives: The aims of this study were to describe vitamin D status in the Generation R study, a large multiethnic cohort of 6-yold children in The Netherlands, and to examine sociodemographic, lifestyle, and dietary determinants of vitamin D deficiency. Methods: We measured serum 25-hydroxyvitamin D [25(OH)D] concentrations in 4167 children aged 6 y and defined deficiency following recommended cutoffs. We examined the associations between subject characteristics and vitamin D deficiency with the use of multivariable logistic regression analyses. Results: Serum 25(OH)D concentrations ranged from 4 to 211 nmol/L (median: 64 nmol/L), with 6.2% of the children having severely deficient (
The Journal of Nutrition Nutritional Epidemiology
Vitamin D Deficiency in School-Age Children Is Associated with Sociodemographic and Lifestyle Factors1–3 Trudy Voortman,4,6,8* Edith H van den Hooven,4,8 Annemieke C Heijboer,7 Albert Hofman,4 Vincent WV Jaddoe,4–6 and Oscar H Franco4 Departments of 4Epidemiology and 5Pediatrics, and 6The Generation R Study Group, Erasmus MC, University Medical Center, Rotterdam, The Netherlands; and 7Department of Clinical Chemistry, VU University Medical Center, Amsterdam, The Netherlands
Background: There is concern about a reemergence of vitamin D deficiency in children in developed countries. Objectives: The aims of this study were to describe vitamin D status in the Generation R study, a large multiethnic cohort of 6-yold children in The Netherlands, and to examine sociodemographic, lifestyle, and dietary determinants of vitamin D deficiency. Methods: We measured serum 25-hydroxyvitamin D [25(OH)D] concentrations in 4167 children aged 6 y and defined deficiency following recommended cutoffs. We examined the associations between subject characteristics and vitamin D deficiency with the use of multivariable logistic regression analyses. Results: Serum 25(OH)D concentrations ranged from 4 to 211 nmol/L (median: 64 nmol/L), with 6.2% of the children having severely deficient (
