Eur J Nucl Med Mol Imaging (2015) 42:905–915 DOI 10.1007/s00259-015-3018-5

ORIGINAL ARTICLE

Volumetric assessment of recurrent or progressive gliomas: comparison between F-DOPA PET and perfusion-weighted MRI Francesco Cicone & Christian P. Filss & Giuseppe Minniti & Camilla Rossi-Espagnet & Annalisa Papa & Claudia Scaringi & Norbert Galldiks & Alessandro Bozzao & N. Jon Shah & Francesco Scopinaro & Karl-Josef Langen

Received: 11 December 2014 / Accepted: 5 February 2015 / Published online: 7 March 2015 # Springer-Verlag Berlin Heidelberg 2015

Abstract Purpose To compare the diagnostic information obtained with 6-[18F]-fluoro-L-3,4-dihydroxyphenylalanine (F-DOPA) PET and relative cerebral blood volume (rCBV) maps in recurrent or progressive glioma. Methods All patients with recurrent or progressive glioma referred for F-DOPA imaging at our institution between May 2010 and May 2014 were retrospectively included, provided

Francesco Cicone and Christian P. Filss contributed equally to this work. F. Cicone (*) : A. Papa : F. Scopinaro Unit of Nuclear Medicine, Sant’Andrea Hospital, Rome, Italy e-mail: [email protected] F. Cicone : G. Minniti : A. Papa : C. Scaringi : F. Scopinaro Department of Surgical and Medical Sciences and translational Medicine, Faculty of Medicine and Psychology, BSapienza^ University of Rome, Rome, Italy F. Cicone : C. P. Filss : N. Galldiks : N. J. Shah : K.

Volumetric assessment of recurrent or progressive gliomas: comparison between F-DOPA PET and perfusion-weighted MRI.

To compare the diagnostic information obtained with 6-[(18)F]-fluoro-L-3,4-dihydroxyphenylalanine (F-DOPA) PET and relative cerebral blood volume (rCB...
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