Electrophoresis 2014, 35, 2687
2687
Editorial Enantioseparations 2014 Enantioselective analysis is required for quality control of chiral drugs, agrochemicals, food additives and fine chemicals during their production, storage and application. In addition, better understanding of chirality may contribute to the advancement of our knowledge about non-covalent intermolecular interactions, supramolecular chemistry, materials chemistry, etc. Therefore, analytical techniques for recognition of chirality and its change during the processes in nature and industry are urgently required. Capillary electromigration techniques combining CE and CEC, as well as other liquidphase separation and some lab-on a chip technologies have found their place among the techniques used for enantiomeric purity determination of various materials and for following various enantioselective processes. The unique separation mechanism of CE perfectly complementing other separation techniques in combination with high peak efficiency, flexibility, low cost, less environmental impact, etc. are very advantageous for solving some complex separation problems. Electrokinetically driven flow has certain advantages for propulsion of small volumes (in nanoliter per minute range) trough micro- and nanochannals (direction, precise flow control, absence of a backpressure, etc.). All of these taken together contribute to further development of electromigration-based enantioseparation techniques that is illustrated with a collection of review and research articles published in this special issue of Electrophoresis on enantioseparations. The issue opens with 4 review papers summarizing current developments in this field followed by 12 research papers on new chiral selectors and methodologies, 4 research papers on separation mechanisms and 5 research papers on bioanalytical and pharmaceutical applications of chiral electromigration and liquid-phase separation techniques. Thus, in my opinion the issue represents a well-balanced source for reading by the newcomers as well as for experienced researchers in this field. I would like to express my thanks to the Editor-in-Chief, Prof. Ziad El-Rassi for his support to chiral electromigration and liquid phase separation techniques by providing the opportunity to publish regularly special issues of Electrophoresis on this topic. I am thankful also to all authors for submitting their high-quality works for publication in this issue and all reviewers for their time, efforts and very competent comments. I sincerely hope that this special issue of Electrophoresis will contribute to further advancement of our knowledge and motivate us for new scientific achievements in this field.
Bezhan Chankvetadze
Prof. Bezhan Chankvetadze Institute of Physical and Analytical Chemistry School of Exact and Natural Sciences Tbilisi State University
C 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
www.electrophoresis-journal.com
2687
Editorial Enantioseparations 2014 Enantioselective analysis is required for quality control of chiral drugs, agrochemicals, food additives and fine chemicals during their production, storage and application. In addition, better understanding of chirality may contribute to the advancement of our knowledge about non-covalent intermolecular interactions, supramolecular chemistry, materials chemistry, etc. Therefore, analytical techniques for recognition of chirality and its change during the processes in nature and industry are urgently required. Capillary electromigration techniques combining CE and CEC, as well as other liquidphase separation and some lab-on a chip technologies have found their place among the techniques used for enantiomeric purity determination of various materials and for following various enantioselective processes. The unique separation mechanism of CE perfectly complementing other separation techniques in combination with high peak efficiency, flexibility, low cost, less environmental impact, etc. are very advantageous for solving some complex separation problems. Electrokinetically driven flow has certain advantages for propulsion of small volumes (in nanoliter per minute range) trough micro- and nanochannals (direction, precise flow control, absence of a backpressure, etc.). All of these taken together contribute to further development of electromigration-based enantioseparation techniques that is illustrated with a collection of review and research articles published in this special issue of Electrophoresis on enantioseparations. The issue opens with 4 review papers summarizing current developments in this field followed by 12 research papers on new chiral selectors and methodologies, 4 research papers on separation mechanisms and 5 research papers on bioanalytical and pharmaceutical applications of chiral electromigration and liquid-phase separation techniques. Thus, in my opinion the issue represents a well-balanced source for reading by the newcomers as well as for experienced researchers in this field. I would like to express my thanks to the Editor-in-Chief, Prof. Ziad El-Rassi for his support to chiral electromigration and liquid phase separation techniques by providing the opportunity to publish regularly special issues of Electrophoresis on this topic. I am thankful also to all authors for submitting their high-quality works for publication in this issue and all reviewers for their time, efforts and very competent comments. I sincerely hope that this special issue of Electrophoresis will contribute to further advancement of our knowledge and motivate us for new scientific achievements in this field.
Bezhan Chankvetadze
Prof. Bezhan Chankvetadze Institute of Physical and Analytical Chemistry School of Exact and Natural Sciences Tbilisi State University
C 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
www.electrophoresis-journal.com
