JID VisualDx Quiz

JID VisualDx Quiz: October 2014 Jose E. Ollague1 and Robert S. Kirsner1 Journal of Investigative Dermatology (2014) 134, e21. doi:10.1038/jid.2014.336

JID and Logical Images, Inc., have cooperated to offer the JID VisualDx Quiz, incorporating diagnostic images from VisualDx’s vast database. Questions relate to the image as well as to selected articles in JID, which are listed after the questions. Answers will be posted as supplementary material. We hope you enjoy this challenge.

Image appears with permission from VisualDx. © Logical Images, Inc.

QUESTIONS 1.  What is your diagnosis?  a. Lichen planus.  b. Scar.  c. Keloid.  d. Dermatofibroma.  e. Sarcoidosis.

Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, Florida, USA

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© 2014 The Society for Investigative Dermatology

www.jidonline.org

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JID VisualDx Quiz

2.  Which of the following is true about mesenchymal stem cells?   a.  They reduce scar formation.   b.  They improve scar strength.   c.  They induce a change in the type of collagen deposition.   d.  They induce proinflammatory cytokines.   e.  All of the above. 3.  Which factors play a role in the mechanism of action of mesenchymal stem cells?  a. Caspase-3.   b.  Tumor necrosis factor-α-stimulated gene/protein 6.  c. IL-6α galactosidase A.   d.  Transforming growth factor-β1.   e.  All of the above.

TOPIC ARTICLE Questions 2 and 3 refer to the following article: Liu S, Jiang L, Li H et al. (2014) Mesenchymal stem cells prevent hypertrophic scar formation via inflammatory regulation when undergoing apoptosis. J Invest Dermatol 134:xxx–xx

Answers are available as supplementary material at http://dx.doi.org/10.1038/jid.2014.336. Additional images related to this condition and the differential diagnosis may be found at http://info.visualdx.com/l/11412/2014-08-27/wgc27

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Journal of Investigative Dermatology (2014), Volume 134

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JID VisualDx quiz: October 2014. Scar.

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