Brief Reports KINGELLA KINGAE DNA IN LANGERHANS CELL HISTIOCYTOSIS OF BONE Nawal El Houmami, MD,* Grégory Dubourg, MD,† Philippe Minodier, MD,‡ Arnauld Verschuur, MD, PhD,§ Corinne Bouvier, MD, PhD,¶ Jean-Luc Jouve, MD, PhD,* Didier Raoult, MD, PhD,† and Pierre-Edouard Fournier, MD, PhD† Abstract: Langerhans cell histiocytosis of bone is a rare pediatric neoplastic disorder of unclear pathogenesis. We report the case of a 3-year-old girl who presented with Langerhans cell histiocytosis of the ilium in which Kingella kingae was detected. Our findings argue for the search for K. kingae by polymerase chain reaction in children with Langerhans cell histiocytosis of bone. Key Words: Kingella kingae, Langerhans cell histiocytosis, osteomyelitis, infectious disease, pediatrics Accepted for publication August 14, 2014. From the * Department of Pediatric Orthopedics, University La Timone Children’s Hospital; †URMITE “Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes,” UM63, CNRS 7278, IRD 198, Inserm 1095; ‡Department of Pediatrics, Emergency Medicine, University North Hospital; §Department of Pediatric Oncology, La Timone Children’s Hospital; and ¶Department of Pathology, University La Timone Hospital, Aix-Marseille University, APHM Public Hospitals of Marseille, Marseille, France. The work was funded by the IHU Méditérannée foundation. The authors have no conflicts of interest to disclose. Address for correspondence: Nawal El Houmami, MD, Service de Chirurgie pédiatrique et orthopédique, Hôpital des Enfants—La Timone, 264, Rue SaintPierre, 13385 Marseille, Cedex 5, France. E-mail: [email protected]. Copyright © 2014 Wolters Kluwer Health, Inc. All rights reserved. DOI: 10.1097/INF.0000000000000527

CASE REPORT A previously healthy 3-year-old girl was admitted in the Department of Pediatric Orthopedics of our institution due to limping of the left lower limb for 6 weeks. At presentation, no fever was noted, and the physical examination and past medical history were unremarkable. Blood testing showed ESR value of 43 mm/h and CRP