NOTE ON MALARIAL FEVER. By Surgeon-Major M. D.

O'Connell,

m.d.,

Army Medical Department. Remittent fever

and

Ague together

under the title of

For this

fever.

they

are

are

With these

classed

usually

paroxysmal"

classification, however,

not appear to be sound.

that

"

malarial

or

the

do

reasons

exceptions, viz.% by side ;

found at times to exist side

that in both there is increase of temperature; that occasionally one disease is said to run or change into the other, and that both

are said to yield to there little reason to quinine, appears by consider that they own a common origin. If these exceptions are examined separately they will perhaps appear less convincing than they seem at first sight. As to the fact that they are at times found ist. side by side, it may be said that it is important but not conclusive. Formerly Typhus and Enteric were found side by side, and were from this and other

treatment

believed

to own

thought Many other

to be

reasons

fact

were

fever.

common

diseases exist side

this considered

not from

a

origin,

and in

different forms of the to

by side,

same

but

be different forms of

are

one

disease. In both diseases the temperature is raised.

2nd. This

can

scarcely

be considered

these two fevers in

one

class.

temperature charts of both be are seen

they

there is

an

to differ

a

reason for

That in

widely.

placing

Moreover, if typical placed side by side one

disease

intermission of temperature and in the remission appears to separate them most

other only a widely and distinctly. As regards remission of temperature, it is known, since the use of charts became

general,

disease

running

that there is an

daily remission is $rd. is

seen

into

a

scarcely

uncomplicated

any febrile

course in

which

a

not the rule.

It is said that to pass into a

quotidian,

tertian, and vice

remittent fever intermittent and then While not prepare

occasionally versa.

a

288

THE INDIAN MEDICAL GAZETTE.

this is

to say that

not so, I have never seen a

tempersupport this statement. Moreover, if such chart be produced, it is no more a proof that ague and remittent fever are different forms of

one

ed its maximum of

would

which

chart

ature

than

disease,

But if the three Presidencies be taken

Bengal

forms

of

one

in almost From my is

have

as

efficacious in remittent fever

is in ague. An attempt is often made to

it

as

enormous

the mala-

result must be the

some

diseases in The

one

extreme

they

whether

same

the

quantity first

insignificant. It may be seen of the reasons for uniting these two or

class

reasons

for

apparent than real. on them as distinct and

are more

looking

widely different diseases sideration.

that

are

Some of them

not

are

as

unworthy of confollows, viz., the

relative prevalence, the period of maximum prevalence, relative mortality, and liability to recurrence. i st.

Relative prevalence.?Ague is

a

very

common

disease, while remittent fever is comparatively rare. In the Report of the Sanitary Commissioner with the Government of India for 1882, it may be seen that amongst European troops there were 28,271 admissions for ague, and only 625 for remittent fever. This indicates that these diseases do not arise from

single poison 2nd.

or

Period

disease

of

a

cause.

maximum

quoted

prevalence.?Although

it is

seen

the very fact of

with whom

be

a

strong

reason

but that the of natives India, is especially amongst from the state of ill health produced by rebe

doubt, however,

no

state

of

that ague attain-

debility

least inter

in which the

disease will prove fatal, but that remittent fever kills of itself.

current

4th.

gives

Liability

recurrence.?This undoubtedly looking on ague and

to

the strongest evidence for

remittent fever

essentially different diseases.

as

One attack of ague predisposes and renders more liable to another. In fact recurrence is characteristic of the disease. one

attack

With remittent fever it is to

seems

confer

a

protective

the

system against a recurrence of Maclean, whose vast experience enables

with great in

unhealthy

that attacks

posed

to

liability

the

so :

not

power

on

disease.

him to

speak

" This says of remittent fever : countries is often the first form of fever

authority, new

comers, but

such

are

seldom

ex-

second attacks ; in other words, there is less to a recurrence of the disease than in the

intermittent form," Vol.

II.,

that

one

page

(Quain's Dictionary of Medicine, 1334). He does not, however, say

attack of remittent fever protects from

a

subsequent attack of ague. During eleven years' experience of Indian fevers I can

only

call to mind

remittent fever

statistics shew that both diseases often prevail at the For instance, same time, yet it is not invariably so. in the Report above

who

men

from ague amongst

attacks of ague. Perhaps it would be simpler kills by reducing its victims to an

peated

in the system, and therefore the

introduced be large then that

specific poisons

few medical

a

occur

to say that ague

fiftieth remittent fever, by supposing that they receive the poison in different quantities. But in putting forward this explanation it is apparently forgotten

multiply indefinitely

death

a

seen

can

mortality,

poison

that it is characteristic of

In

uncommon.

caused 32 deaths.

proving fatal would questioning the diagnosis.

There

undoubtedly

explain why

fever is not

the disease for

should produce in one man ague and in remittent another fever, or more correctly, why it should produce in forty-nine cases ague and in the

rial

never

European soldiers,

class.

one

but

mortality,?Ague seldom kills,

from remittent

much less prevalent, Perhaps, also, there are not

uniting ague Quinine is useful any fever, in other words, it is antipyretic. own experience I cannot say that quinine

and remittent fever in

while

the month in which both

as

although

cannot be considered a reason for

This

separately,

result,

same

Report above referred to ague is credited with a total of four deaths in India, while remittent fever,

useful in both diseases.

is found

Quinine

re-

the

disease.

4th.

the

Bombay give

Relative

3rd. death

Yet it is not suggested and sometimes tertian ague. that because enteric fever sometimes ends as a typical be

and

Madras give September fevers are most prevalent.

perature in the fourth week of uncomplicated enteric fever is often exactly similar to that of quotidian

must both

October, while

in

mittent fever reached its maximum in August. '1 his to European troops in the whole of India*

fever is proof that enteric fever and ague are different forms of the same disease. The course of tem-

intermittent fever, they

prevalence

refers

chart of enteric

typical

a

1884.

[October,

on

one

more

patient

than

who suffered from

one

occasion.

This

is in my experience the exception which proves I have seen small-pox attack a native the rule. case

twice within twelve months, still this does not lead me to doubt that, as a rules, it protects against a woman

FRACTURE OF PATELLA TREATED BY METALLIC SUTURES.

October, 1884.]

second attack. As to recurrence then, ague and remittent fever differ widely, and in this respect remittent fever rather resembles scarlatina, measles and

small-pox, &c. it scarcely admits of doubt that a remitdistinct from Enteric fever, and usually

However, fever, as

tent

of from five to fifteen

it is

not

frequently

Occasionally considerable

days' duration, exists, although

seen.

in

occur

cases

in

difficulty

which

giving

there may be

the fever

a

name, but

affirm that the study of disease only is full of difficulties, and that modified forms of

to say

this is

to

diseases

different

essentially

each other that

error

be expected. One may meet that he is

an

in

old friend

recognized

at

diagnosis

with

times

simulate

so

must now and

then

altered in appearance difficulty, if at all; and it so

may have happened to many men, to shake hands with a perfect stranger under the impression that they were

greeting an

So it is with disease.

old friend.

It is not with remittent

fever, however,

that this

particularly, but with ague. There are perhaps good grounds for believing that a specific malarial (as distinct from climatic) cause of the disease paper deals

exists.

Whatever this

bacillus, microbe,

or

cause

poison,

of disease be

it is

probably

remittent fever and not of ague. connected with climatic

is proposed in influences can the normal

a

or

subsequent

poison.

to

(See

of

Ague is so obviously influences, that it

paper to consider if these so to interfere with

be shewn at times

physiological our

cause

seasonal

functions of the

cause intermittent fever and

calling

called,?

the

body

its sequelre,

as

to

without

assistance the hypothetical malarial Indian Medical Gazette, August

also

ist, 1882.) Ainbala.

0

289

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