In fever countries most advantage is to be insistance on strict general hygiene, by interdicting alcohol, and by prescribing the diet most compatible with health. Never give " " quinine as preventive unless it is clearly indicated by the nature of the country, and not even then, unless its use can be combined with the more truly saving measures noted above. It is believed in many feverish parts that a good meal should be made on rising in the morning. This is said to be a custom in Holland. Excellent cocoa is said to be supplied by the Commissariat (when you find it) on this Expedition. Thickened by being kept for a few minutes at the boil, it is almost at once ready on rising, and seems an ideal filling food for the purpose. I have only seen strong coffee and soup recommended for the purpose as yet, but thin liquids

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have not the distending filling power so essential, and with such, some solid food is necessary. QUININE AND MALARIAL FEVER IN The quinine used in army hospitals is the INDIA. i.m.s. sulphate only. There has been recently published By Subgeon-Major G. M. SHEW AN, a table of many quinine salts showing the solubiThe subject is suggested by the constant referand the percentage of quinine in each. From lity ence to me about quinine as a preventive here, in I that I extracted only the following :? the advance part of the Chitral Expedition, and in I The basic sulphate, 74*31 per cent, quinine, and disa country for the most part out of malarial range. solves in 581 parts water at 15? C. The neutral sulphate, 59'12 per cent, quinine, and Many of the natives have enlarged spleens, and the Dir Valley is said to be most feverish, but dissolves in 11 parts water at 15? C. The basic chlorohydrate, 81"71 per cent, quinine, and in the autumn only. dissolves in 23'73 parts water at 15? C. for the purpose The neutral chlorohydrate, 81*61 per cent, quinine, By obstinately refusing quinine and dissolves in 0-66 parts water at 15? C. at this season I may have given offence to officers, and that quinine disco capsules, pilules and It is seen from this that the is " " perles are being furtively swallowed wholesale, the most soluble, and also the mostchlorohydrate rich in alkaloid. of the from I conclude peculiar prevalence depresIn the " preventive" use of quinine, great sion and debilitated colon among friends (fatigue solubility is not so desirable. Continuous slow of an overworked, irritated digestive canal). " is more to be sought for. " absorption use of Apart the in Faith preventive quinine is from its richness in alkaloid, however, it is found fast on the wane, and though perhaps a majority to be much less irritating to the digestive canal, of Indian physicians may yet not agree, I can an the support at hand, advantage which, from what has been already with state here fearlessly is apparent. said, that for the soldier in India, this use of the drug personal experience?practice with other By The British soldier above is positively dangerous. salts?I am not inclined to support the holding all is strongly attached to a full meat diet. that in use the sulphate should be displaced; Nothing can shake his belief that he is dependant but thearmy use of into quinine hypodermic and coming in all all circumstances on it under climates. use, the neutral chlorohydrate must be used. Stint the meat and, as a rale, he will replace it, Here is a formula for injection generally in use Hence where possible, with spirituous drink. in the French army :? debilitated a deranged, of digestive frequency 10 gr. Chlorohydrate neutre de quinine canal weakening him and "making him prey to the Eau bouillde et sterilisee 20 gr. " and to bilious fevers infection even so-called Chaque seringue contiendra 50 centigrammes de sel more to be feared than malaria. de quinine. " " Here, then, the preventive use of quinine Shortly noticing the modes of administration is called for, it may be said, but fortunately it is of sulphate alone in the army I would state that understood that of now doses being clearly " the army pill, which fortunately seems to be preventive" against quinine effective as a to be secretion proof. malaria tend to cause this very condition of the disappearing, has appeared Coated the with made right proportions of pills bowel, and certainly most seriously aggravate that are said of milk and to be sugar gum-arabic set condition, once up. don't know soluble I the excipient of but enough, that is established with it Further, many people the service pill referred to. this so-called preventive use of quinine renders The tabloids now in use in field to hospitals are insensitive them more or less strong curative very good. needed in an attack. doses when ...

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Quinine and Malarial Fever in India.

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