Duplex Doppler Sonography in Renal Parenchymal Disease Histopathologic Correlation
Gerhard H. Mostbeck, MD,* Renate Kain, MD,t Reinhold Mallek, MD,* Kurt Derfler, MD,* Reinhard Walter, MD,* Lieselotte Havelec, PhD,§ DimiterTscholakoff, MD*
To evaluate the histopathologic changes influencing Doppler measurements of the resistive index (RI) in renal arteries in renal parenchymal diseases, 68 kidneys in 34 consecutive patients with various forms of renal parenchymal diseases were studied by duplex Doppler ultrasound (duplex US) immediately before percutaneous renal biopsy. The RI, renal length, and renal cortical echogenicity were correlated with the amount of glomerular, interstitial, and vascular changes graded on a scale from 0 to 100. The renal vascular resistance and therefore the RI are significantly correlated with the prevalence of arteriolosderosis, glomerular sclerosis, arteriosclerosis, edema, and focal interstitial fi-
I
n patients with renal parenchymal diseases, as· sessment of sonographic parameters such as renal length, renal cortical echogenicity, or distinctness of the corticomedullary boundary does not allow us to distinguish specific types of renal medical disorders.•-• Additionally, increased cortical echogenicity has proved to be an insensitive indicator of renal paren·· ~· & Quantitative duplex Doppler ultrachymal disease. sound (duplex US) using the resistive index (RI) is widely used in evaluating renal allograft dysfunction.1-14 However, results concerning sensitivity and specificity of the RI in identifying the cause of dysfunction are contradictory.M. u -14 An increased RI has Received June 21, 1990, from the •Division of Radiology ~ toivision of Nephrology, First Department of Medicine; 'Institute of Pathology; and 'Institute for Medical Statistics and Documentation, University of Vienna Hospital, Vienna, Austria. Revised manuscript accepted for publication September 19, 1990. Address correspondence and reprint requests to Dr. G. Mostbeckt Department of Radiology, First Medical Clinic, University of Vienna Hospitals, Lazarettgasse 14. A-1097 Vienna, Austria.
brosis. There was no significant difference of the RI in five groups of different renal parenchymal diseases. Of 34 patients, 24 presented with an RI
Gerhard H. Mostbeck, MD,* Renate Kain, MD,t Reinhold Mallek, MD,* Kurt Derfler, MD,* Reinhard Walter, MD,* Lieselotte Havelec, PhD,§ DimiterTscholakoff, MD*
To evaluate the histopathologic changes influencing Doppler measurements of the resistive index (RI) in renal arteries in renal parenchymal diseases, 68 kidneys in 34 consecutive patients with various forms of renal parenchymal diseases were studied by duplex Doppler ultrasound (duplex US) immediately before percutaneous renal biopsy. The RI, renal length, and renal cortical echogenicity were correlated with the amount of glomerular, interstitial, and vascular changes graded on a scale from 0 to 100. The renal vascular resistance and therefore the RI are significantly correlated with the prevalence of arteriolosderosis, glomerular sclerosis, arteriosclerosis, edema, and focal interstitial fi-
I
n patients with renal parenchymal diseases, as· sessment of sonographic parameters such as renal length, renal cortical echogenicity, or distinctness of the corticomedullary boundary does not allow us to distinguish specific types of renal medical disorders.•-• Additionally, increased cortical echogenicity has proved to be an insensitive indicator of renal paren·· ~· & Quantitative duplex Doppler ultrachymal disease. sound (duplex US) using the resistive index (RI) is widely used in evaluating renal allograft dysfunction.1-14 However, results concerning sensitivity and specificity of the RI in identifying the cause of dysfunction are contradictory.M. u -14 An increased RI has Received June 21, 1990, from the •Division of Radiology ~ toivision of Nephrology, First Department of Medicine; 'Institute of Pathology; and 'Institute for Medical Statistics and Documentation, University of Vienna Hospital, Vienna, Austria. Revised manuscript accepted for publication September 19, 1990. Address correspondence and reprint requests to Dr. G. Mostbeckt Department of Radiology, First Medical Clinic, University of Vienna Hospitals, Lazarettgasse 14. A-1097 Vienna, Austria.
brosis. There was no significant difference of the RI in five groups of different renal parenchymal diseases. Of 34 patients, 24 presented with an RI
