THE JOURNAL OF PEDIATRICS
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of the Canadian Paediatric Trigger Tool. BMJ Qual Saf 2011;20: 416-23. 20. Brennan TA, Leape LL, Laird NM, Hebert L, Localio AR, Lawthers AG, et al. Incidence of adverse events and negligence in hospitalized patients: results of the Harvard Medical Practice Study I. N Engl J Med 1991;324: 370-6. 21. Kovacevic A, Dehghan A, Filannino M, Keane JA, Nenadic G. Combining rules and machine learning for extraction of temporal expressions and events from clinical narratives. J Am Med Inform Assoc 2013;20:859-66. 22. Bennett JW, Glasziou PP. Computerised reminders and feedback in medication management: a systematic review of randomised controlled trials. Med J Aust 2003;178:217-22.
Vol. 165, No. 3 23. Garg AX. Effects of computerized clinical decision support systems on practitioner performance and patient outcomes. J Am Med Assoc 2005;293:1223-8. 24. Embi PJ, Leonard AC. Evaluating alert fatigue over time to EHR-based clinical trial alerts: findings from a randomized controlled study. J Am Med Inform Assoc 2012;19:e145-8. 25. Lin CP, Payne TH, Nichol WP, Hoey PJ, Anderson CL, Gennari JH. Evaluating clinical decision support systems: monitoring CPOE order check override rates in the Department of Veterans Affairs’ Computerized Patient Record System. J Am Med Inform Assoc 2008;15:620-6. 26. van der Sijs H, Aarts J, van Gelder T, Berg M, Vulto A. Turning off frequently overridden drug alerts: limited opportunities for doing it safely. J Am Med Inform Assoc 2008;15:439-48.
50 Years Ago in THE JOURNAL OF PEDIATRICS Sarcoidosis among Children in Utah and Idaho Beier FR, Lahey ME. J Pediatr 1964;65:350-9
F
rom their practice, the authors summarized the demographic, clinical, laboratory, pathology, treatment, and outcomes of 8 children with sarcoidosis. Another 120 pediatric cases were summarized from the literature. The majority of the children (59%) had lung involvement, 48% had skin and eye involvement, 35% had lymphadenopathy, whereas only 27% had musculoskeletal disease. All children were diagnosed by tissue biopsy showing noncaseating granulomas with exclusion of other conditions. The authors could not find a common denominator for their patients (although all were of Northern European ancestry) nor for those in other series, including a family history of sarcoidosis. The majority of children improved spontaneously, with several patients requiring courses of corticosteroid treatment. One difference between the series of Beier and Lahey and the other series they quote is that the disease onset was
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of the Canadian Paediatric Trigger Tool. BMJ Qual Saf 2011;20: 416-23. 20. Brennan TA, Leape LL, Laird NM, Hebert L, Localio AR, Lawthers AG, et al. Incidence of adverse events and negligence in hospitalized patients: results of the Harvard Medical Practice Study I. N Engl J Med 1991;324: 370-6. 21. Kovacevic A, Dehghan A, Filannino M, Keane JA, Nenadic G. Combining rules and machine learning for extraction of temporal expressions and events from clinical narratives. J Am Med Inform Assoc 2013;20:859-66. 22. Bennett JW, Glasziou PP. Computerised reminders and feedback in medication management: a systematic review of randomised controlled trials. Med J Aust 2003;178:217-22.
Vol. 165, No. 3 23. Garg AX. Effects of computerized clinical decision support systems on practitioner performance and patient outcomes. J Am Med Assoc 2005;293:1223-8. 24. Embi PJ, Leonard AC. Evaluating alert fatigue over time to EHR-based clinical trial alerts: findings from a randomized controlled study. J Am Med Inform Assoc 2012;19:e145-8. 25. Lin CP, Payne TH, Nichol WP, Hoey PJ, Anderson CL, Gennari JH. Evaluating clinical decision support systems: monitoring CPOE order check override rates in the Department of Veterans Affairs’ Computerized Patient Record System. J Am Med Inform Assoc 2008;15:620-6. 26. van der Sijs H, Aarts J, van Gelder T, Berg M, Vulto A. Turning off frequently overridden drug alerts: limited opportunities for doing it safely. J Am Med Inform Assoc 2008;15:439-48.
50 Years Ago in THE JOURNAL OF PEDIATRICS Sarcoidosis among Children in Utah and Idaho Beier FR, Lahey ME. J Pediatr 1964;65:350-9
F
rom their practice, the authors summarized the demographic, clinical, laboratory, pathology, treatment, and outcomes of 8 children with sarcoidosis. Another 120 pediatric cases were summarized from the literature. The majority of the children (59%) had lung involvement, 48% had skin and eye involvement, 35% had lymphadenopathy, whereas only 27% had musculoskeletal disease. All children were diagnosed by tissue biopsy showing noncaseating granulomas with exclusion of other conditions. The authors could not find a common denominator for their patients (although all were of Northern European ancestry) nor for those in other series, including a family history of sarcoidosis. The majority of children improved spontaneously, with several patients requiring courses of corticosteroid treatment. One difference between the series of Beier and Lahey and the other series they quote is that the disease onset was
